ABC | Volume 114, Nº5, May 2020

Original Article Torralba et al. HEART, TIMI, and GRACE scores for MACE prediction Arq Bras Cardiol. 2020; 114(5):795-802 Figure 2 – ROC curves for the HEART, TIMI and GRACE scores. 1.0 1.0 0.8 0.8 0.6 0.6 0.4 0.4 0.2 0.2 0.0 0.0 Sensitivity Specificity C statistic: HEART score = 0.937 (CI 95%: 0.917–0.957) TIMI score = 0.844 (CI 95%: 0.811–0.876) GRACE score = 0.797 (CI 95%: 0.758–0.836) Figure 3 – Calibration belt test for HEART score 0.0 0.0 0.2 0.2 0.4 0.4 0.6 0.6 0.8 0.8 1.0 1.0 Estimated MACE probability Observed MACE rate N = 519 P < 0.001 Confidence level Under the bisector Over the bisector 80% 95% NEVER NEVER 0.15–1.00 0.19–0.99 Statistical analysis: Castellanos JC; Writing of the manuscript: Torralba F, Navarro A, Ortiz C, Isaza N, Isaza D; Critical revision of the manuscript for intellectual content: Torralba F, Navarro A, Castellanos JC, Ortiz C, Isaza N, Isaza D. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Fundación Cardioinfantil under the protocol number 20- 2017. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 800