ABC | Volume 114, Nº5, May 2020

Original Article Ribeiro Junior & Fernandes Effect of Activity on Hypertension Arq Bras Cardiol. 2020; 114(5):755-761 analyses that included PA-O, both with a duration scale and an intensity scale of load handling. The most active workers in this form were more effectively protected against HBP, even with age, gender and overweight adjustments. Motivation for these analyses with PA-O levels was based on the recent literature discussion about the “paradoxical effect” of PA-O on blood pressure. 30 According to researchers, individuals subjected to high PA-O levels would have a higher risk of HBP. 14,31 It is possible that occupations that demand the use of large muscle groups, such as garbage collection, although they may exhibit physical fatigue, do not seem to show association with HA, as proposed in the paradoxical effect. In this study, active work was always protective against this condition, particularly when associated with PA-D and PA-L. Although PA-L is deemed to be one of the main non- pharmacological treatments for HBP, 32-34 according to the present study, PA-L alone may not compensate for insufficient PA for the purposes of effective HBP control. Being active in only one form and inactive in the other two forms showed a positive association with HBP. Few studies explore PA-D alone. The data on this form of PA do not seem to show an association with HBP. Nevertheless, when combined with the practice of PA in other forms, PA-D can produce beneficial effects on HBP control. Although the present study showed the cumulative effect of low PA in its different forms as a risk factor for HBP, no interaction was found between these forms (not even in the additive model). A similar fact was observed in another study, which also revealed a cumulative effect of different forms of PA, but no interaction among them. 7 Interaction analysis to explore sedentary behavior and/or time spent in front of the TV in determining chronic diseases in adults seems to be a promising approach. 35 In addition to PA accumulation in the different forms being a protective factor, accumulation during the various stages of life can further improve health indicators. 36 In this study, PA levels were obtained from self-report and not measured directly through cardiac monitors, accelerometers, pedometers and frequency meters. Despite the tendency to consider direct measures more valid than self-reporting, the first have been questioned as the gold standard in Occupational Epidemiology. Due to their cost and instrument calibration requirements, direct measurements are usually obtained from short time sampling and, in the case of PA-O, during a small sample of the workday schedule. This is particularly relevant in studies with populations whose occupational activities involve high variability over the course of a workday, since this factor may limit the validity of direct measurements. In other words, direct measurements that sample a small proportion of the workday may not be representative of the whole working day. 37 In the cross-sectional study design, the main bias is the prevalence. Therefore, reverse causality cannot be ruled out, i.e., it is not possible to determine whether the higher prevalence of HBP among less active individuals is due to a sedentary life or whether they were already hypertensive before moving on to a more sedentary life. However, since HBP is a chronic disease, treatment can ensure its control, but not its cure. Thus, this type of bias can be minimized, and cross-section may be an appropriate option for study design. The study population is predominantly composed of young workers, but the results obtained and described for the prevalence of HBP among the different age groups allow for comparisons with other populations, provided that each age group is observed. Conclusion This study showed that lower activity levels in the different forms of PA was a risk factor associated with HBP in this population. Since other studies demonstrate a similar line of evidence, the results of this study can be considered valid. From these studies, it was considered that the investigation of PA, a modifiable factor in the occurrence of HBP, cannot waive its different forms, otherwise it would imply a methodological error when classifying subjects who are active at work or at home as inactive individuals, based on the form of leisure. Interventions should be planned in the occupational environment, so workers have the opportunity to express what HBP means for themselves, and get access to study results in order to stimulate changes in habits and to increase the role of workers in electing active leisure activities and highlighting the importance of PA-O. New research should enhance the study of PA in order to bring new evidence on its role in HBP. Author contributions Conception and design of the research and Statistical analysis: Ribeiro Junior UES, Fernandes RCP; Acquisition of data and critical revision of the manuscript for intellectual content: Fernandes RCP; Analysis and interpretation of the data and writing of the manuscript: Ribeiro Junior UES. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the thesis of master submitted by Uelito Everaldo Souza Ribeiro Junior, from Universidade Federal da Bahia. 759

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