ABC | Volume 114, Nº4, Suplement, April 2020

Case Report Silva et al. Transthyretin Amyloidosis - without the need for biopsy Arq Bras Cardiol 2020; 114(4Suppl.1):8-12 be ATTR. 2,3,10 Amyloidosis, notably that associated with transthyretin, is a disease that requires a high degree of clinical suspicion for diagnosis. Its early diagnosis is essential, as it is a cause of polyneuropathy and/or cardiomyopathy that, if left untreated, evolves progressively to death. 1 Author contributions Writing of the manuscript: Silva TO; Critical revision of the manuscript for intellectual content: Silva TO, Darzé ED, Ritt LEF, Almeida ALC, Ximenes A. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associated with any thesis or dissertation work. Ethics approval and consent to participate This article does not contain any studies with human participants or animals performed by any of the authors. Figure 3 – Simplified flowchart for the diagnosis of amyloidosis. 11