ABC | Volume 114, Nº3, March 2020

Original Article Silva et al. Warfarin therapy in NVAF patients in Brazil Arq Bras Cardiol. 2020; 114(3):457-466 Figure 2 – INR and TTR results. A. Measurement distribution per INR range. B. Patient distribution per TTR range. 0.3% 1.6% 1.8% 4.2% 9.1% 17.0% 24.3% 20.4% 10.9% 6.4% 4.3% 7.1% 18.7% 27.1% 22.0% 11.7% 6.4% 6.7% 6000 5000 4000 3000 2000 1000 0 0 50 100 150 200 250 300 350 30.0% 25.0% 20.0% 15.0% 10.0% 5.0% 0 30.0% 25.0% 20.0% 15.0% 10.0% 5.0% 0 # measurements # patients % patients % measurements 0.5–1.0 1.0–1.5 1.5–2.0 2.0–2.5 2.5–3.0 3.0–3.5 3.5–4.0 >4.0 INR Range 0%–10% 11%–20% 21%–30% 31%–40% 41%–50% 51%–60% 61%–70% 71%–80% 81%–90% 91%–100% TTR Range A) B) Figure 3 – Bleeding rate per TTR quartile. 5.9 4.6 12.4 11.1 4.6 1.6 4.2 10.3 6.9 10.9 18 16 14 12 10 8 6 4 2 0 Q1 (n = 303) Q2 (n = 306) Q3 (n = 305) Q4 (n = 306) Total (n = 1,220) Minor bleeds Major bleeds Bleeding rate per TTR quartile 462