ABC | Volume 114, Nº3, March 2020

Original Article Vaz et al. RIAM – registry of acute myocardial infarction Arq Bras Cardiol. 2020; 114(3):446-455 Figure 1 – Improvement and expansion flowchart for the multicenter Registry of Acute Myocardial Infarction. Source: Lucidchart. Available in: https://www.lucidchart.com Development of a data collection form (Case report form - CRF) The electronic data form – Case Report Form (CRF) was developed using REDCap. Figure 2 shows the necessary steps to set up the CRF. The steps for the creation of a CRF followed the guidelines of the software. Within the third step, a pilot test was run with patients randomly chosen from the Microsoft Access™ RIAM database for the purpose of CRF validation. Automated export procedures for data download for programs such as Microsoft Excel and common statistical packages such as SPSS, SAS and R were performed to ensure software security and reliability. Registry Expansion to other reference centers using the institutional REDCap Invited centers were selected because of the existence of interventional cardiology sectors with STEMI treatment 24 hours a day, 7 days a week. Initially, a meeting was held with local coordinators of other centers (called Principal Investigator - PI) to present the proposed expansion. Afterwards, the invited centers were informed of the participation processes via e-mail. The institutions that agreed to participate in the multicenter phase of the RIAM Registry are located in many regions in Brazil (Figure 4): 1. Instituto de Cardiologia - Fundação Universitária de Cardiologia (IC/FUC), Porto Alegre, Rio Grande do Sul, Brazil – Coordinating Center; 2. Instituto de Cardiologia do Distrito Federal (IC-DF), Brasília, Distrito Federal, Brazil. 3. Hospital e Maternidade Marieta Konder Bornhausen (HMMKB), Itajaí, Santa Catarina, Brazil; 4. Hospital Geral de Caxias do Sul (HGCS), Caxias do Sul, Rio Grande do Sul, Brazil; 5. Hospital UNIMED, Caxias do Sul, RioGrande do Sul, Brazil; 6. Hospital da Cidade de Passo Fundo (HCPF), Passo Fundo, Rio Grande do Sul, Brazil; 7. Hospital Universitário de Santa Maria (HUSM), Santa Maria, Rio Grande do Sul, Brazil; 8. ICOR - Instituto do Coração de Santa Maria (ICOR), Santa Maria, Rio Grande do Sul, Brazil; RIAM registry protocols were created to include participating centers to then start multicenter expansion. These protocols were sent by email in PDF (Portable Document Format) for later printing, completion and signature. Once signed, the protocols were sent back to the coordinating center via scanner, email, mail or personally delivered to the RIAM registry coordinators. Training - SOP (Standard Operating Procedure) Before data collection, the principal investigator and their researchers received an email with a link to access REDCap and an individual username and password, which upon receipt may request the creation of a new password, ensuring the confidentiality of the researcher in institutional REDCap. 448

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