ABC | Volume 114, Nº3, March 2020

Original Article Creation and Implementation of a Prospective and Multicentric Database of Patients with Acute Myocardial Infarction: RIAM Jacqueline Vaz, 1 Anibal Pereira Abelin, 1,2, 3 Marcia Moura Schmidt, 1 Pedro Piccaro de Oliveira, 1 Carlos A. M. Gottschall, 1 Clarissa Garcia Rodrigues, 1 Alexandre Schaan de Quadros 1 Instituto de Cardiologia, 1 Porto Alegre, RS – Brazil Universidade Federal de Santa Maria (UFSM), 2 Santa Maria, RS – Brazil Universidade Franciscana (UNIFRA), 3 Santa Maria, RS – Brazil Mailing Address: Alexandre Schaan de Quadros • Instituto de Cardiologia - Av. Princesa Isabel, 395. Postal Code 90620-000, Porto Alegre, RS – Brazil E-mail: quadros.pesquisa@gmail.com Manuscript received January 15, 2019, revised manuscript April 03, 2019, accepted May 15,2019 DOI: https://doi.org/10.36660/abc.20190036 Abstract Background: Multicenter registries representing the real world can be a significant source of information, but few studies exist describing the methodology to implement these tools. Objective: To describe the process of implementing a database of ST-segment elevation acute myocardial infarction (STEMI) at a reference hospital, and the application of this process to other centers by means of an online platform. Methods: In 2009, our institution implemented an Registry of Acute Myocardial Infarction (RIAM), with the prospective and consecutive inclusion of every patient admitted to the institution who received a diagnosis of STEMI. From March 2014 to April 2016, the registries were uploaded to a web-based system using the REDCap software and the registry was expanded to other centers. Upon subscription, the REDCap platform is a noncommercial software made available by Vanderbilt University to institutions interested in research. Results: The following steps were taken to improve and expand the registry: 1. Standardization of variables; 2. Implementation of institutional REDCap (Research Electronic Data Capture); 3. Development of data collection forms (Case Report Form - CRF); 4. Expansion of registry to other reference centers using the REDCap software; 5. Training of teams and participating centers following an SOP (Standard Operating Procedure). Conclusion: The description of the methodology used to implement and expand the RIAM may help other centers and researchers to conduct similar studies, share information between institutions, develop new health technologies, and assist public policies regarding cardiovascular diseases. (Arq Bras Cardiol. 2020; 114(3):446-455) Keywords: Myocardial Ischemia/physiopathology; Cardiovascular Diseases/mortality; Myocardial Infarction/ physiopathology; Multicenter Study; Database; Public Health Policy . Introduction Ischemic cardiomyopathy (IC) is one of the leading causes of death in the world. 1 According to DATASUS (Brazilian Basic Health Indicators and Data), acute myocardial infarction (AMI) is the leading cause of death from heart disease in Brazil, but information on clinical characteristics and treatment received by most patients with AMI in the country are poorly known. 2 Many international registries of acute coronary syndromes have been published, which include the collaboration of some Brazilian centers: 3,4 however, only a few nationwide studies reporting AMI treatment outcomes have been published so far. 5,6 The management of registry data demands technological support for their storage in computerized databases, with software that provides safe, reliable and easy access to data. Research Electronic Data Capture (REDCap) is a software for clinical data capture and storage which is widely used for clinical research. It is a fast and secure web application currently used by 3,175 institutions in 128 countries. 7 Few studies have reported in detail the methodology of recording clinical data in cardiology, and references describing the steps for the implementation of a clinical registry and for the use of REDCap as an online platform are scarce. 8-11 The Instituto de Cardiologia do Rio Grande do Sul/ Fundação Universitária de Cardiologia (IC/FUC) started the Registry of Acute Myocardial Infarction (RIAM) in 2009, with consecutive, prospective and uninterrupted data collection since it was implemented. 12 A national ST-segment elevation myocardial infarction (STEMI) registry derived from the expansion of a registry such as RIAM could be a source of representative data for this pathology in Brazil. The aim of this study is to describe the implementation of a STEMI database in a reference hospital as well as the use of an online platform to apply it to other centers across the national territory. Methods This section describes the steps taken to migrate the RIAM database from Microsoft Access into the online system and 446