ABC | Volume 114, Nº3, March 2020

Review Article Oliveira The Top 10 Original Articles Published in the ABC Cardiol and in the RPC in 2019 Arq Bras Cardiol. 2020; 114(3):564-570 of them had three or more concomitant CVR factors. These data show the importance of the overall assessment of CVR in hypertensive patients, and, once again, the urgent need to implement preventive strategies to improve the control of CVR factors in Portugal. The first author of both studies was our colleague Pedro Marques da Silva, a remarkable physician, who left an indelible mark on Cardiovascular Medicine. His passing in early 2020 brought us great sorrow. This was a tremendous loss for cardiology in Portugal. Difficulty controlling CVR factors in children and adolescents has also been observed. A study with 1254 children and adolescents from southern Brazil (female sex, 55%; age range: 7-17 years) has assessed the relationship between dyslipidemia, cultural factors and cardiorespiratory fitness (CRF). The cultural factors were assessed by use of a self-reporting questionnaire, and the CRF levels, by use of the 12-minute walk/run test, which consisted in covering the longest possible distance on a previously established track for 12 minutes. The authors have reported a dyslipidemia prevalence of 42%, which was associated with female sex and low CRF levels. On multivariate analysis, dyslipidemia was associated with children, but not with adolescents, as well as with overweight and obesity. In addition, sedentary commuting to and from school, too much time spent watching TV, female sex, and overweight/obesity were associated with isolated components of the lipid profile. The authors have emphasized the need for early interventions that promote healthy life habits among children. 5 The ELSA-Brazil study, 6 assessing 15105 public servers (age range: 35-74 years) from six teaching and research institutions of the Brazilian southern, southeastern and northeastern regions, has assessed the magnitude of the association between abdominal adiposity, defined based on different diagnostic indicators [waist circumference (WC), waist-to-hip ratio (WHR), conicity index , lipid accumulation product (LAP), visceral adiposity index (VAI)], and carotid intima-media thickness (cIMT), a marker of subclinical atherosclerosis and predictor of myocardial infarction and stroke. By using multiple logistic regression, the authors have shown an important association of abdominal adiposity, diagnosed by use of WC, with cIMT in both sexes (men: OR = 1.47; 95% CI: 1.22- 1.77; women: OR = 1.38; 95% CI: 1.17-1.64). Abdominal adiposity, identified by the indicators WC, WHR, LAP and VAI, in women showed a 0.02-mm effect on cIMT (WC: 0.025, 95% CI: 0.016-0.035; WHR: 0.026, 95% CI: 0.016-0.035; LAP: 0.024, 95% CI: 0.014-0.034; VAI: 0.020, 95% CI: 0.010-0.031). The results observed reinforce the importance of abdominal adiposity, represented by WC, especially in men, as a simple marker of abdominal adiposity associated with subclinical atherosclerosis. In addition, subclinical atherosclerosis seems to be associated with systemic inflammation in patients with resistant arterial hypertension (RAH). In a convenience sample of 224 hypertensive patients, half of themwith RAH, an inflammatory score (IS) was established, comprising the measurement of plasma pro-inflammatory and anti-inflammatory cytokines and adipokines, TNF-alpha, interleukins (IL)-6, -8, -10, leptin Table 1 – List of the top ten articles published in the Arquivos Brasileiros de Cardiologia in 2019 Author Title of the article and link Faria AP et al. 7 Proposta de um Escore Inflamatório de Citocinas e Adipocinas Plasmáticas Associado à Hipertensão Resistente, mas Dependente dos Parâmetros de Obesidade http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000400383&lng=pt&nrm=iso&tlng=pt Dippe Jr. et al. 18 Estudo de Perfusão Miocárdica em Obesos sem Doença Cardíaca Isquêmica Conhecida http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000200121&lng=en&nrm=iso&tlng=pt Reuter CP et al. 5 Relação entre Dislipidemia, Fatores Culturais e Aptidão Cardiorrespiratória em Escolares http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000600729&lng=en&nrm=iso&tlng=pt Villela PTM et al. 9 A Preferência ao Sal está Relacionada à Hipertensão e não ao Envelhecimento http://www.scielo.br/scielo.php?pid=S0066-782X2019005015104&script=sci_arttext&tlng=pt Barros MVL et al. 27 Alteração Contrátil Segmentar Ventricular Esquerda é Preditor Independente de Cardiotoxicidade em Pacientes com Câncer de Mama em Tratamento Quimioterápico http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000100050&lng=pt&nrm=iso&tlng=pt Kiyose AT et al. 28 Comparação de Próteses Biológicas e Mecânicas para Cirurgia de Válvula Cardíaca: Revisão Sistemática de Estudos Controlados Randomizados http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000300292&lng=en&nrm=iso&tlng=pt Eickemberg M et al. 6 Indicadores de Adiposidade Abdominal e Espessura Médio-Intimal de Carótidas: Resultados do Estudo Longitudinal de Saúde do Adulto - ELSA-Brasil http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000300220&lng=en&nrm=iso&tlng=pt Effting PS et al. 8 Exercício Resistido Modula Parâmetros de Estresse Oxidativo e Conteúdo de TNF-α no Coração de Camundongos com Obesidade Induzida por Dieta http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019000500545&lng=es&nrm=iso&tlng=pt Avila WS et al. 29 Gravidez em portadoras de cardiopatias congênitas complexas. Um constante desafio http://www.scielo.br/scielo.php?pid=S0066-782X2019005019101&script=sci_arttext&tlng=pt Barbosa JE et al. 17 Perfil da Expressão do mRNA do Nrf2, NF-κB e PPARβ/δ em Pacientes com Doença Arterial Coronariana http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2019005001205&lng=en&nrm=iso&tlng=pt 565