ABC | Volume 114, Nº2, February 2020

Original Article Vieira et al. Evaluation myocardial ischemia with iFR Arq Bras Cardiol. 2020; 114(2):256-264 Figure 5 – ROC curve for the iFR (instantaneous wave-free ratio); a sensitivity of 0.57 and 1-specificity of 0.88 was observed for the iFR cut-off point of 0.87, obtained from the classification tree. AUC: area under the curve. 1.00 1.00 0.75 0.75 0.50 0.50 0.25 0.25 0.00 0.00 1 - Specificity Sensitivity AUC = 0.7933 study was achieved – we showed the additional contribution of the iFR to the therapeutic decision making in moderate and severe coronary disease, when the correlation between obstructive coronary artery disease and myocardial ischemia is not clearly defined by conventional diagnostic methods. Author contributions Conception and design of the research: Ferreira MCM, Oliveira GMM; Acquisition of data: Vieira HCA, Ferreira MCM, Nunes LC, Cardoso CJF; Analysis and interpretation of the data: Vieira HCA, Ferreira MCM, Nascimento EM, Oliveira GMM; Statistical analysis: Nascimento EM, Oliveira GMM; Writing of the manuscript: Vieira HCA, Ferreira MCM, Oliveira GMM; Critical revision of the manuscript for intellectual content: Ferreira MCM, Nascimento EM, Oliveira GMM. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. Ethics approval and consent to participate This article does not contain any studies with human participants or animals performed by any of the authors. 262