ABC | Volume 114, Nº2, February 2020

Update Update of the Brazilian Guideline on Nuclear Cardiology – 2020 Arq Bras Cardiol. 2020; 114(2):325-429 Table 32 – Exam types and main scintigraphy findings of new applications of nuclear cardiology Pathology Exam Main findings TTR CA (hereditary or wild) Scintigraphy with 99m Tc-pyrophosphate Shows moderate to severe radiotracer uptake; high accuracy for detection of TTR form (PPV 100%); allows for early diagnosis; reflects extent of deposit; prognostic marker Light chain CA Scintigraphy with 99m Tc-pyrophosphate Absence of uptake or slight cardiac uptake Sarcoidosis FDG- 18 F - PET/CT Cardiac hypermetabolism demonstrating active in-flammation Myocardial perfusion scintigraphy Persistent myocardial hy-poperfusion suggestive of tissue damage due to in- flammation Endocarditis FDG- 18 F - PET/CT Hypermetabolism in areas of infection Scintigraphy with marked leukocytes High uptake in areas of infection CA: cardiac amyloidosis; PPV: positive predictive value; TTR: transthyretin amyloidosis. our context. They have the capability to detect functional alterations in these pathologies, indicating whether a disease is or active or not and assisting in therapeutic monitoring. Cardiologists’ knowledge of these applications will be essential to their proper use and to the dissemination of these diagnostic methods. 411

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