ABC | Volume 114, Nº2, February 2020

Update Update of the Brazilian Guideline on Nuclear Cardiology – 2020 Arq Bras Cardiol. 2020; 114(2):325-429 Table 23 – New markers for cardiovascular risk stratification • High-sensitivity CRP • Apolipoprotein B • Glomerular filtration rate • Microalbuminuria • Ankle-brachial index • Family history • Functional capacity • Mean carotid intima thickness • Coronary calcium score CRP: C-reactive protein. integration of all available pretest clinical data and data obtained during the performance of the stress or associated stimulus test within the denominated incremental prognostic value. In this sense, Bayes’ theory of conditional probability or the application of Bayesian principles assists in decision making by establishing that the risk of an event occurring after a test is influenced by the sensitivity and specificity of an applied method, as well as the pretest prevalence of the disease, all of which are incorporated into the estimation of post-test probability for characterization of myocardial ischemia and, consequently, CAD (Figure 12). 129,130 In this way, the diagnostic ability of a test is related to the population type selected, and it is may create tendencies or biases. For example, the selective referral of patients with Figure 11 – Calculation of 10-year risk of fatal cardiovascular event, in populations of countries with high cardiovascular risk, considering the risk factors of age, sex, smoking, total cholesterol, and systolic blood pressure. Cart from the SCORE (Systematic Coronary Risk Evaluation) Study. The color scale varying from red to green corresponds to percent risk over 10 years, described in the upper part of the Table. Adapted from Piepoli MF et al. 120 Women Men Non-smoker Smoker Non-smoker Smoker Systolic blood pressure Cholesterol (mmol/L) Age 350