ABC | Volume 114, Nº1, January 2019

Original Article Almeida et al. Left ventricular remodeling in primary care Arq Bras Cardiol. 2020; 114(1):59-65 1. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol. 1986;57(6):450-8. 2. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the FraminghamHeart Study. N Engl J Med.1990;322(22):1561-6. 3. Schvartzman PR, Fuchs FD, Mello AG, Coli M, Schvartzman M, Moreira, LB. Valores normais de medidas ecocardiográficas. Um estudo de base populacional. Arq Bras Cardiol. 2000;75(2):107-10. 4. Vakili BA, Okin PM, Devereux RB. Prognostic implications of left ventricular hypertrophy. AmHeart J. 2001;141(3):334-41. 5. Desai RV, Ahmed MI, Marjan M, Aban IB, Zile MR, Ahmed A. Natural history of left ventricular geometry in community-dwelling older adults without heart failure during seven years of follow-up. Am J Cardiol. 2011;107(2):321-4. 6. KonstamMA, Kramer DG, Patel AR, MaronMS, Udelson JE. Left ventricular remodeling in heart failure current concepts in clinical significance and assessment. J Am Coll Cardiol Img. 2011;4(1):98-108. 7. Yancy CW, JessupM, Bozkurt B, Butler J, Casey DE, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the AmericanCollegeofCardiologyFoundation/AmericanHeartAssociationTask Force on Practice Guidelines. J AmColl Cardiol. 2013;62(16):e147-239. 8. Mayet J, Hughes A. Cardiac and vascular pathophysiology in hypertension. Heart. 2003;89(9):1104-9. 9. Jorge AL, Rosa ML, Martins WA, Correia DM, Fernandes LC, Costa JA, et al. The prevalence of stages of heart failure in primary care: a population-based study. J Cardiac Fail. 2016;22(2):153-7. 10. 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Gori M, LamCS, Gupta DK, Santos AB, Cheng S, Shah AMet al. Sex-specific cardiovascular structure and function inheart failurewith preserved ejection fraction.Eur J Heart Fail. 2014;16(5):535-42. 15. Borlaug BA, Redfield MM, Melenovsky V, Kane GC, Karon BL, Jacobsen SJ, et al. Longitudinal changes in left ventricular stiffness: a community based study. Circ Heart Fail 2013;6(5):944–952. 16. Salton CJ, Chuang ML, O’Donnell CJ, Kupka MJ, Larson MG, Kissinger KV, et al. Gender differences and normal left ventricular anatomy in an adult population free of hypertension. A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort. J Am Coll Cardiol 2002;39(6):1055–60. 17. BombigMTN,PóvoaR.Cardiopatiahipertensiva:aspectosepidemiológicos, prevalência e fator de risco cardiovascular. Rev Bras Hipertens. 2008;15(2):75-80. 18. OliverasA,ArmarioP,SierraC,ArroyoJA,Hernández-del-ReyR,VazquezS,et al. Urinary albumin excretion at follow-up predicts cardiovascular outcomes insubjectswithresistanthypertension.AmJHypertens.2013;26(9):1148-54. References to therapy may have influenced the remodeling patterns in females, and such adherence was not measured. Conclusion One third of individuals attending primary care between the ages of 45 and 99 years, in the sample analyzed, had LVR and were at risk for developing HF. Altered albumin/ creatinine ratios in urine was associated with eccentric hypertrophy, indicating an early relations hip between cardiac and renal dysfunction. Author contributions Conception and design of the research: Almeida RCM, Jorge AJL, Rosa MLG, Martins WA; Acquisition of data: Jorge AJL, Leite AR, Correia DMS, Chermont S, Lugon JR; Analysis and interpretation of the data: Almeida RCM, Jorge AJL, Mesquita ET, Martins WA; Statistical analysis: Rosa MLG; Writing of the manuscript: Almeida RCM, Jorge AJL, Rosa MLG, Chermont S, Martins WA; Critical revision of the manuscript for intellectual content: Jorge AJL, Rosa MLG, Mesquita ET, Lugon JR, Martins WA. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the thesis of master submitted by Roberto de Castro Meirelles Almeida, from Universidade Federal Fluminense. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Universidade Federal Fluminense under the protocol number CAAE: 0077.0.258.000-10 . All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 64

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