ABC | Volume 114, Nº1, January 2019

Original Article Almeida et al. Left ventricular remodeling in primary care Arq Bras Cardiol. 2020; 114(1):59-65 Table 1 – Demographic and clinical characteristics of the selected individuals characterized by left ventricular remodeling patterns Variables Normal geometry n = 423 Eccentric hypertrophy n = 186 Concentric hypertrophy n = 14 Concentric remodeling n = 13 p-value (*) Age (years) 56 (50-64) 58 (47-70) 63 (55-71) 61 (53-71) < 0.0001 Female (%) 57.4 71.5 78.6 53.8 0.005 Non-white (%) 63.5 63 57 61.5 0.812 SBP (mmHg) 133.7 (121-147) 133(115.5-134.9) 144.5 (126-175) 135.6 (120.2-156) 0.148 DBP (mmHg) 82.3 (74.3-90.0) 76 (73.5-91) 83.5 (75.9-91.5) 80 (72-90) 0.385 PP (mmHg) 517 (42-60) 51 (36-59) 60 (47-59) 55 (46-67) 0.004 HR (bpm) 70 (63-78) 72 (65-80) 74 (64-83) 69 (61-77) 0.468 BMI (kg/m 2 ) 27.2 (24,5-30.6) 28.6 (19.4-35.8) 26.8 (23.4-30.6) 27.7 (24.3-30.7) 0.881 Glycemia (mg/dL) 101 (92-113) 107 (92-125) 104 (92-125) 100 (92-115) 0.734 GFR (mL/min) 83.4 (71.7-96.1) 84.1 (74.6-92.8) 67.7 (53.6-85.0) 82.3 (67.2-94.1) 0.021 Uric acid (mg/dL) 5.2 (4.3-6.4) 4.5 (3.8-5.9) 4.6 (3.9-5.9) 5.0 (4.1-6.1) 0.266 Cholesterol (mg/dL) 214 (188-243) 201 (157-221) 208 (184-250) 215 (185-245) 0.507 Alb/Creat (mg/g) 9.3 (5.5-18.7) 8.0 (5.2-170.1) 16.2 (9.9-42.9) 11.8 (6.2-38.9) 0.018 sod/creat in urine 120.9 (77-160) 108.3 (48-200) 145.4 (77-235) 126.2 (89-185) 0,205 BNP (pg/mL) 14 (10-25) 17 (11-41) 35 (14-120) 21 (11-42) < 0.0001 Albuminuria (mg) 10.5 (5.4-20.8) 8.5 (4.4-65.4) 13.7 (5.8-30.8) 12.8 (7-34.5) 0.049 Hypertension (%) 54.6 63.4 71.4 53.8 0.150 Diabetes (%) 24.3 23.7 50.0 30.8 0.159 CAD (%) 8.7 7.5 14.3 15.4 0.657 Obesity (%) 28.7 32.3 28.6 46.2 0.488 SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; HR: heart rate; BMI: body mass index; GFR: estimated glomerular filtration rate; Alb/Creat: albumin/creatinine ratio; sod/creat: sodium/creatinine ratio; BNP: type B natriuretic peptide; CAD: coronary artery disease; (*) p = difference between the patterns of remodeling performed with the Kruskall-Wallis test 1-way ANOVA for multiple comparisons (all pairs) and Pearson's chi-squared test for differences of proportion. Table 2 – Echocardiographic parameters of the selected individuals characterized by left ventricular remodeling patterns Variables Normal geometry n = 423 Eccentric hypertrophy n = 186 Concentric hypertrophy n = 14 Concentric remodeling n = 13 p-value (*) LVEF (%) 61 (58-65) 63 (58-64) 59 (50-64) 60 (56-63) 0.01 LVMi (g/m 2 ) 82.8 (72.2-92.0) 84 (70.7-93.4) 120 (105.6-150.71) 116.3 (102.4-127.3) < 0.0001 LAVi (ml/m 2 ) 20.8 (17.1-24.5) 18 (14-22.3) 23.6 (19.2-33.1) 22.6 (19.2-27.5) < 0.0001 EDVi (ml/m 2 ) 60.1 (51.8-67.2) 41.7 (36.4-49.4) 60.5 (52.1-75.9) 74.7 (67.7-83.2) < 0.0001 E’(cm/s) 10(8-12) 12(7.5-13) 7.7(6-10.6) 9(7-11) < 0.0001 E (cm/s) 64 (54-76) 70(52-93) 68(51-75) 63 (52-78) 0.532 A (cm/s) 65 (53-81) 76(59-99) 69(56-98) 71 (57-86) 0.242 E/A ratio 1.0 (0.7-1.3) 1.1 (0.6-1.3) 0.9 (0.7-1.1) 0.8 (0.7-1.2) 0.003 E/E’ ratio 6.4 (5.3-7.7) 7.1 (4.7-8.7) 8.0 (5.7-10.0) 7.1 (5.7-8.4) 0.008 SWT (mm) 8(7-8) 9(8-10) 10(10-12) 9(8-9) < 0.0001 LVDD (mm) 47 (44-50) 40 (34.5-41.5) 43.5 (41.7-47.8) 52 (49-54,2) < 0.0001 PWT (mm) 8(7-8) 9(8-10) 10(10-12) 8(8-9) < 0.0001 LVEF: left ventricular ejection fraction; LVMi: indexed left ventricular mass; LAVi: indexed left atrial volume; EDVi: indexed end-diastolic volume; E´: mitral annular early diastolic velocity; E: early mitral inflow velocity; A: peak mitral inflow velocity at atrial contraction ; LVDD: LV diastolic diameter; SWT: septal wall thickness; PWT: posterior wall thickness (*)= p value - the difference between the patterns of remodeling performed with Kruskall-Wallis test 1-way ANOVA for multiple comparisons (all pairs). 61