ABC | Volume 114, Nº1, January 2019

Original Article Gomes et al. Characterization of dyslipidemias in the youth Arq Bras Cardiol. 2020; 114(1):47-56 Limitations of the study One of the limitations concerns the fact that the evaluated database is of secondary origin, with possible inaccuracies in the insertion of demographic data throughout all the processes. We are aware of the continued use of the quality control standards of the Brazilian Society of Clinical Pathology by the Municipal Laboratory of Campinas, which supplies the laboratory data. In addition, since it was a cross-sectional study, it was not possible to evaluate the incidence of cases of dyslipidemia. Conclusion This study shows the high frequency of atherogenic dyslipidemias in adolescents, children and infants attended in Campinas, with a greater distribution in the less favored socioeconomic regions, indicating the need for a regionalized focus during the development of public health programs for the prevention of early and adulthood CVD, including proper handling and treatment of dyslipidemias. Acknowledgements To the Secretaria de Saúde de Campinas for the availability of the database for the study, to the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); protocol 481863/2011-7, and to the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); protocol 2006/60585-9 for the research grants. The authors also are grateful to the Espaço da Escrita - Pró-Reitoria de Pesquisa - UNICAMP - for the translation of the manuscript to English. This study was part of the masters’degree of Erica I. L. Gomes. Author contributions Conception and design of the research, Acquisition of data and Obtaining financing: Faria EC; Analysis and interpretation of the data: Gomes EIL, Faria EC; Statistical analysis: Gomes EIL; Writing of the manuscript and Critical revision of the manuscript for intellectual content: Gomes EIL, Zago VHS, Faria EC. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was funded by FAPESP process nº 2006/60585-9. Study Association This article is part of the thesis of master submitted by Érica Ivana Lázaro Gomes, fromUniversidade Estadual de Campinas. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Unicamp under the protocol number CAAE: 86627418.3.0000.5404 Nº do parecer: 2.662.289. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. 1. WorldHealthOrganization (WHO). Cardiovascular diseases (CVDs). 2017; Available from: http://www.who.int/en/news-room/fact-sheets/detail/ cardiovascular-diseases-(cvds). 2. Sociedade Brasileira de Cardiologia . Cardiômetro: Mortes por doenças cardiovasculares no Brasil. 2015; Available from: http://www.cardiometro . com.br/. 3. Faludi AA, Izar MC, Saraiva JF, Chacra AP, Bianco HT, Afiune Neto A, et al. Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose – 2017. Arq Bras Cardiol. 2017;109(2 Suppl 1):1-76. 4. Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, et al. Global and regional patterns in cardiovascular mortality from1990 to 2013. Circulation. 2015;132(17):1667-78. 5. Brasil.Leis, Decretos. Lei n. 8.069, de 13 de julho de 1990, e legislação correlata. Dispõe sobre o Estatuto da Criança e do Adolescente. DOU de 16/07/1990 – ECA; Brasilia,2012. 6. Napoli C, D’Armiento FP, Mancini FP, Postiglione A, Witztum JL, Palumbo G, et al. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J Clin Invest. 1997;100(11):2680-90. 7. Zachariah JP, Johnson PK. Pediatric LipidManagement An Earlier Approach. Endocrinol Metab Clin North Am. 2014;43(4):981-92. 8. Faria-Neto J, Bento V, Baena C, Olandoski M, Goncalves L, Abreu G, et al. ERICA: prevalence of dyslipidemia in Brazilian adolescents. Rev Saude Publica. 2016;50(Suppl 1):10s. 9. Faria EC, Dalpino FB, Takata R. Lípides e lipoproteínas séricos em crianças e adolescentes ambulatoriais de umhospital universitário público. Rev Paul Pediatr. 2008;26(1):54-8. 10. Xavier HT, Izar MC, Faria Neto JR, Assad MH, Rocha VZ, Sposito AC, et al. V Brazilian Guidelines on Dyslipidemias and Prevention of Atherosclerosis. Arq Bras Cardiol. 2013;101(4 Suppl 1):1-20. 11. Kwiterovich PO. Recognition and management of dyslipidemia in children and adolescents. J Clin Endocrinol Metab. 2008;93(11):4200-9. 12. Johansen IC, Carmo RL, Alves LC. Desigualdade social intraurbana: implicações sobre a epidemia de dengue em Campinas, SP, em 2014. Cad Metrop. 2016;18(36):421-40. 13. São Paulo. Estado. Secretaria de Saúde de Campinas. Estrutura - SUS Campinas. Campinas: Prefeitura Municipal de Campinas; 2017 [Citado 2018 abr 16] Disponível em: http://www.saude.campinas.sp.gov.br/saude/. 14. BerensonGS, Srinivasan SR, BaoW, NewmanWP, Tracy RE, WattigneyWA. Association betweenmultiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med. 1998;338(23):1650-6. References 54