ABC | Volume 114, Nº1, January 2019

Original Article Adar et al. Aortic calcification and non-dipper blood pressure Arq Bras Cardiol. 2020; 114(1):109-117 1. Tigen K, Karaahmet T, Fotbolcu H, Gurel E, Cevik C, Gecmen C, et al. The influence of dipper and nondipper blood pressure patterns on left ventricular functions in hypertensive patients: a tissueDoppler study. Turk Kardiyol Dem Ars. 2009;37(2):101-6. 2. Della Mea P, Lupia M, Bandolin V, Guzzon S, Sonino N, Vettor R, et al. Adiponectin, insulin resistance, and left ventricular structure in dipper and nondipper essential hypertensive patients.Am J Hypertes. 2005;18(1):30-5. 3. Portaluppi F, Montanari L, Massari M, Di Chiara V, Capanna M. Loss of nocturnal decline of blood pressure in hypertension due to chronic renal failure. Am j Hypertens. 1991;4(1 Pt 1):20-6. 4. Ozdemir E, Yildirimturk O, Cengiz B, Yurdakul S, Aytekin S. Evaluation of carotid intima-media thickness and aortic elasticity in patients with nondipper hypertension. Echocardiography. 2014;31(5):663-8. 5. Clement DL, De Buyzere ML, De Bacquer DA, de Leeuw PW, Duprez DA, Fagard RH, et al. Prognostic value of ambulatory blood-pressure recordings in patients with treated hypertension. NEngl J Med. 2003;348(24):2407-15. 6. Ohkubo T, Imai Y, Tsuji I, Nagai K, Watanabe N, Minami N, et al. Prediction of mortality by ambulatory blood pressure monitoring versus screening blood pressure measurements: a pilot study in Ohasama. J Hypertens. 1997;15(4):357-64. 7. Syrseloudis D, Tsioufis C, Andrikou I, Mazaraki A, Thomopoulos C, Mihas C, et al. Association of nighttime hypertension with central arterial stiffness and urinary albumin excretion in dipper hypertensive subjects. Hypertens Res. 2011;34(1):120-5. 8. Jerrard-Dunne P, Mahmud A, Feely J. Circadian blood pressure variation: relationship between dipper status and measures of arterial stiffness. J Hypertens. 2007;25(6):1233-9. 9. Zieman SJ, Melenovsky V, Kass DA. 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Systolic Hypertension in Europe Trial Investigators. JAMA 1999;282(6):539-46. 19. Fagard RH, Celis H, Thijs L, Staessen JA, Clement DL, De Buyzere ML, et al. Daytime and nighttime blood pressure as predictors of death and cause-specific cardiovascular events in hypertension. Hypertension. 2008;51(1):55-61. 20. Garcia-Ortiz L, Gomez-Marcos MA, Martin-Moreiras J, Gonzalez-Elena LJ, Recio-Rodriguez JI, Castano-Sanchez Y, et al. Pulse pressure and nocturnal fall in blood pressure are predictors of vascular, cardiac and renal target organdamage inhypertensivepatients (LOD-RISKstudy).BloodPressMonit. 2009;14(4):145-51. 21. Ohkubo T, Hozawa A, Yamaguchi J, Kikuya M, Ohmori K, Michimata M, et al. Prognostic significance of the nocturnal decline in blood pressure in individuals with andwithout high 24-h blood pressure: theOhasama study. J Hypertens.. 2002;20(11):2183-9. 22. Mahabala C, Kamath P, Bhaskaran U, Pai ND, Pai AU. Antihypertensive therapy: nocturnal dippers and nondippers. Do we treat them differently? Vasc Health Risk Manag. 2013;9:125-33. References Table 5 – Multivariate analysis for non-dipper blood pressure pattern 95% CI β OR Lower Upper Age 0.015 1.015 0.988 1.043 Body mass index 0.037 1.038 0.989 1.090 Left ventricular mass index 0.006 1.006 0.992 1.019 Hypertension 0.059 1.061 0.664 1.696 Triglyceride -0.003 0.997 0.995 1.000 Presence of aortic arch calcification 1.366 3.919 2.392 6.421 Gender -0.444 0.641 0.405 1.016 Glomerular filtration rate 0.003 1.003 0.979 1.028 CI: confidence interval; OR: odds ratio; β: regression coefficient. 115