ABC | Volume 113, Nº6, December 2019

Original Article Barbosa et al Nrf2, NF- κ B and PPAR β / δ in CAD patients Arq Bras Cardiol. 2019; 113(6):1121-1127 1. Pinho RA, AraújoMC, Ghisi GL, Benetti M. Coronary heart disease, physical exercise and oxidative stress. Arq Bras Cardiol. 2010;94(4):549–55. 2. GoAS, MozaffarianD, Roger VL, Benjamin EJ, Berry JD, BlahaMJ, et al. Heart disease and stroke statistics--2014 update: a report from the AmericanHeart Association. Circulation. 2014;129(3):e28–292. 3. Mack M, Gopal A. Epidemiology, Traditional and Novel Risk Factors in Coronary Artery Disease. Heart Fail Clin. 2016;12(1):1–10. 4. Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, et al. Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119(3):480–6. 5. GomesF,TeloDF,SouzaHP,Nicolau JC,HalpernA,Serrano JrCV.Obesidade e doença arterial coronariana: papel da inflamação vascular. 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Palomer X, Barroso E, Pizarro-Delgado J, Peña L, Botteri G, Zarei M, et al. PPAR β / δ : A Key Therapeutic Target in Metabolic Disorders. Int J Mol Sci. 2018;19(3). pii:E913. References Author contributions Conception and design of the research and Analysis and interpretation of the data: Barbosa JE, Stockler-Pinto MB, Cruz BO, Silva ACT, Anjos JS, Mesquita CT, Mafra D, Cardozo LFMF; Acquisition of data and Writing of the manuscript: Barbosa JE, Stockler-Pinto MB, Cruz BO, Silva ACT, Anjos JS, Cardozo LFMF; Statistical analysis and Obtaining financing: Stockler‑Pinto MB, Mafra D, Cardozo LFMF; Critical revision of the manuscript for intellectual content: Barbosa JE, Stockler‑Pinto MB, Mesquita CT, Mafra D, Cardozo LFMF. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding Th i s s t ud y wa s s uppo r t ed b y Coo r de n a ç ã o de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) – Finance Code 001, Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) (Process E-26/203.269/2017) and (Process E_05/2016E_05/2016), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Study Association This article is part of the thesis of master submitted by Jaqueline Ermida Barbosa, from Universidade Federal Fluminense. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Universidade Federal Fluminense under the protocol number 826.041 CAAE 35035414.8.0000.5243. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 1125