ABC | Volume 113, Nº4, October 2019

Original Article Rodrigues et al. Myocardial strain measured by speckle tracking Arq Bras Cardiol. 2019; 113(4):737-745 1. There is no room for complacency 53% of all people living with HIV being on antiretroviral therapymeans that another 17million people withHIV are not Lancet.2017;390(10092):333-428. 2. Prendergast BD. HIV and cardiovascular medicine. Heart 2003; 89(7):793‑800 3. Barbaro G. Cardiovascular manifestations of HIV infection. J R Soc Med. 2001;94(8):384-90. 4. Barbaro G, Fisher SD, Pellicelli AM, Lipshultz SE. The expanding role of the cardiologist in the care of HIV infected patients. Heart. 2001;86(4):365-7. 5. Rerkpattanapipat P, Wongpraparut N, Jacobs LE, Kotler MN. Cardiac manifestations of acquired immunodeficiency syndrome. Arch InternMed. 2000;160(5):602-8. 6. Milei J, Grana D, Fernández Alonso G, Matturi L. Cardiac involvement in acquired immunodeficiency syndrome – a review to push action. Clin Cardiol. 1998;21(7):465-72. 7. Liu YW, Tsai WC, Su CT, Lin CC, Chen JH. Evidence of left ventricular systolic dysfunction detected by automated function imaging in patients with heart failure abd preserved left ventricular ejection fraction. J Card Fail. 2009;15(9):782-89. 8. Choi JO, CHOSW, Song YB, Cho SJ, Song BG, Lee SC, Park SW. Longitudinal 2D strain at rest predicts the presence of left main and three vessel coronary artery disease in patients without regional wall motion abnormality. Eur J Echocardiogr. 2009;10(5):695-701. 9. Jurcut R, Wildiers H, Ganame J, D’hooge J, De Backer J, Denys H, et al. Strain rate imaging detects early cardíaca effects of pegylated liposomal Doxorubicin as adjuvant therapy in elderly patients with breast câncer. J Am Soc Echocardiogr. 2008;21(12):1283-89. 10. Hare JL, Brown JK, Leano R, Jenkins C, Woodward N, Marwick TH. Use of myocardial deformation imaging to detect preclinical myocardial dysfunction before conventional measures in patients undergoing breast cancer treatment with trastuzumab. AmHeart J. 2009;158(2):294-301. 11. Barbaro G. Cardiovascular Manifestations of HIV Infection. Circulation. 2002;106(11):1420-5. 12. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al . Chamber Quantification Writing Group; American Society of Echocardiography’s Guidelines and Standards Committee; European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18(12):1440-63. 13. Mendes L, Silva D, Miranda C, Sá J, Duque L, Duarte N, et al. Impact of HIV infection on cardiac deformation. Rev Port Cardiol. 2014;33(9):501-9. 14. Sims A, Frank L, Cross R, Clauss S, DimockD, Purdy J, et al. Abnormal cardiac strain in children and young adults with HIV acquired in early life. J Am Soc Echocardiogr. 2012;25(7):741-8. 15. Mignot A, Donal E, Zaroui A, Reant P, Salem A, Hamon C, et al. Global Longitudinal Strain as a Major Predictor of Cardiac Events in Patients with Depressed Left Ventricular Function: A Multicenter Study. J Am Soc Echocardiogr. 2010;23(10):1019-24. 16. Marwick TH, Yu CM (eds). Myocardial imaging: tissue Doppler and speckle tracking. Massachusetts: Blackwell Publishing; 2007. p.17-25. 17. Abduch MC, Salgo I, Tsang W, Vieira ML, Cruz V, Lima M, et al. Myocardial Deformation by Speckle Tracking in Severe Dilated Cardiomyopathy. Arq Bras Cardiol. 2012;99(3):834-43 18. Hsue PY. Impact of HIV Infection of diastolic function at left ventricular mass. Circ Heart Fail. 2010;3(1):132-9. References Conclusion The technique of studying myocardial strain by speckle tracking was able to detect early signs of deterioration of myocardial systolic function in HIV-infected patients, regardless of whether or not they were on antiretroviral drugs. Further studies are needed to evaluate HIV-infected patients and to assess the prognostic significance of these abnormalities in these patients. Author contributions Conception and design of the research: Rodrigues RC, Mesquita CT, Setubal S, Azevedo KML. Acquisition of data: Rodrigues RC, Mesquita CT, Azevedo KML. Analysis and interpretation of the data: Rodrigues RC, Mesquita CT, Setubal S, Moscavitch SD, Azevedo KML. Statistical analysis: Rodrigues RC, Mesquita CT, Moscavitch SD, Azevedo KML. Writing of the manuscript: Rodrigues RC, Mesquita CT, Setubal S, Moscavitch SD, Azevedo KML. Critical revision of the manuscript for intellectual content: Rodrigues RC, Mesquita CT, Setubal S, Moscavitch SD, Azevedo KML. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was partially funded by CAPES and Ronaldo Campos Rodrigues. Study Association This article is part of the thesis of master submitted by Ronaldo Campos Rodrigues, from Universidade Federal Fluminense (Hospital Universitário Antônio Pedro). Ethics approval and consent to participate This study was approved by the Ethics Committee of the Hospital Universitário Antônio Pedro under the protocol number HUAP 159/11. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 743