ABC | Volume 113, Nº1, July 2019

Original Article Gil et al Risks scores in acute coronary syndromes Arq Bras Cardiol. 2019; 113(1):20-30 Table 3 – Predictive accuracy and goodness of fit of the scores at predicting in-hospital mortality and comparation with the ProACS risk score In-hospital mortality c-statistics (95% CI) p-value p-value (Hosmer–Lemeshow χ 2 ) Comparing with the ProACS Risk Score ∆ p-value TIMI for STEMI 0.744 (0.695-0.792) < 0.001 0.486 0.165 < 0.0001 PURSUIT 0.775 (0.733-0.817) < 0.001 0.043 0.133 < 0.0001 SRI 0.732 (0.682-0.781) < 0.001 0.23 0.176 < 0.0001 GRACE 0.890 (0.855-0.925) < 0.001 0,298 0.0185 0.0879 EMMACE 0.749 (0.700-0.797 < 0.001 0.566 0.160 < 0.0001 CHA 2 DS 2 -VASc-HS 0.600 (0.543-0.656) 0.001 0,804 0.309 < 0.0001 ACTION Registry–GWTG 0.904 (0.870-0.938) < 0.001 0.041 0.00399 0.6647 C-ACS 0.619 (0.554-0.684) < 0.001 0.003 0.289 < 0.0001 ProACS 0.908 (0.876-0.941) < 0.001 0.031 N/A N/A ∆: difference between the two AUC (area under the curve). TIMI: Thrombolysis in Myocardial Infarction; PURSUIT: Platelet glycoprotein IIb/IIa in Unstable angina: Receptor Suppression Using Integrilin Therapy; Simple Risk Index; GRACE: Global Registry of Acute Coronary Events; EMMACE: Evaluation of the Methods and Management of Acute Coronary Events; C-ACS: Canada Acute Coronary Syndrome. Table 4 – Predictive accuracy and goodness of fit of the scores at predicting in-hospital mortality and comparation with the ProACS risk score, in both STEMI and NSTEMI/UA STEMI In-hospital mortality c-statistics (95% CI) p-value p-value (Hosmer– Lemeshow χ 2 ) Comparing with the ProACS Risk Score ∆ p-value TIMI for STEMI 0.785 (0.720-0.849) < 0.001 0.766 0.139 < 0.0001 PURSUIT 0.809 (0.758-0.861) < 0.001 0.075 0.114 < 0.0001 SRI 0.781 (0.718-0.843) < 0.001 0.011 0.143 < 0.0001 GRACE 0.899 (0.856-0.942) < 0.001 0.603 0.0244 0.0331 EMMACE 0.795 (0.731-0.858) < 0.001 0.392 0.129 < 0.0001 CHA 2 DS 2 -VASc-HS 0.674 (0.596-0.751) < 0.001 0.206 0.250 < 0.0001 ACTION Registry–GWTG 0.911 (0.874-0.948) < 0.001 0.882 0.0127 0.2248 C-ACS 0.620 (0.531-0.708) 0.004 0.005 0.304 < 0.0001 ProACS 0.923 (0.892-0.955) < 0.001 0.821 N/A N/A NSTEMI/UA c-statistics (95% CI) p-value p-value (Hosmer– Lemeshow χ 2 ) Comparing with the ProACS Risk Score ∆ p-value TIMI for STEMI 0.696 (0.624-0.767) < 0.001 0.377 0.202 < 0.0001 PURSUIT 0.742 (0.673-0.810) < 0.001 0.551 0.157 < 0.0001 SRI 0.682 (0.604-0.761) < 0.001 0.078 0.216 < 0.0001 GRACE 0.878 (0.822-0.934) < 0.001 0.566 0.0205 0.2040 EMMACE 0.702 (0.629-0.774) < 0.001 0.376 0.197 < 0.0001 CHA 2 DS 2 -VASc-HS 0.534 (0.448-0.620) 0.453 0.455 0.364 < 0.0001 ACTION Registry–GWTG 0.895 (0.835-0.956) < 0.001 < 0.001 0.00302 0.8411 C-ACS 0.618 (0.522-0.714) 0.009 0.077 0.281 < 0.0001 ProACS 0.898 (0.841-0.956) < 0.001 0.001 N/A N/A ∆: difference between the two AUC (area under the curve). TIMI: Thrombolysis in Myocardial Infarction; PURSUIT: Platelet glycoprotein IIb/IIa in Unstable angina: Receptor Suppression Using Integrilin Therapy; Simple Risk Index; GRACE: Global Registry of Acute Coronary Events; EMMACE: Evaluation of the Methods and Management of Acute Coronary Events; C-ACS: Canada Acute Coronary Syndrome. 25