ABC | Volume 113, Nº1, July 2019

Editorial Gomes et al. Exercise in cardiovascular diseases Arq Bras Cardiol. 2019; 113(1):9-10 1. Stevens B, Pezzullo L, Verdian L, Tomllison J, George A, Bacal F. et al. The economic burden of heart conditions in Brazil. Arq Bras Cardiol. 2018;111(1):29-36. 2. Comitê Coordenador de Cardiologia; Rohde LEP, Montera MW, Bocchi EA, ColanfranceschiAS,FreitasA,FrrazAS,etal.Diretrizbrasileirade insuficiência cardíaca crônica e aguda. Arq Bras Cardiol. 2018;111(3):436-539. 3. Winter SCN, Macedo RM, Francisco JC, santos PC, Lopes APS, Meira LF, et al. et al. Impact of a high-intensity training on ventricular function in rats after acute myocardial infarction. Arq Bras Cardiol. 2018;110(4):373-80. 4. Ghorbanzadeh V, Mohammadi M, Dariushnejad H, Abhari A, Chodanai L, Mohaddes G. Cardioprotective effect of crocin combined with voluntary exercise in rat: Role of Mir-126 andMir-210 in heart angiogenesis. Arq Bras Cardiol. 2017; 109(1):54-62. 5. Naderi R, Mohaddes G, Mohammadi M,Alihemmati A, Khamaneh A, Ghyasi R, et al. The effect of garlic and voluntary exercise on cardiac angiogenesis in diabetes: The role of Mir-126 andMir-210. Arq Bras Cardiol. 2019;112(2):154-62. 6. Gomes MJ, Martinez PF, Campos DHS, Pagan LV, Bonomo C Lima AR, et al. Beneficial effects of physical exercise on functional capacity and skeletal muscle oxidative stress in rats with aortic stenosis-induced heart failure. Oxid Med Cell Longev. 2016;2016:8695716. 7. Pagan LU, Damatto RL, Cezar MD,Lima AR, Bonomo C, Campos DH, et al. Long-term low intensity physical exercise attenuates heart failure development in aging spontaneously hypertensive rats. Cell Physiol Biochem. 2015;36(1):61-74. 8. Gomes MJ, Martinez PF, Pagan LU, Damatto RL, Cezar MDM, Lima Ar, et al. Skeletal muscle aging: Influence of oxidative stress and physical exercise. Oncotarget. 2017;8(12):1235-45. 9. Reyes DRA, Gomes MJ, Rosa CM, Pagan LU, Zanati SG, damatto RL, et al. Exercise during transition from compensated left ventricular hypertrophy to heart failure in aortic stenosis rats. J Cell Mol Med. 2019;23(2):1235-45. 10. Cattadori G, Segurini C, Picozzi A, Padeletti L, Anzá C. Exercise and heart failure: An update. ESC Heart Fail. 2018;5(2):222-32. 11. Gomes MFP, Borges ME, Rossi VA, et al. The effect of physical resistance training on baroreflex sensitivity of hypertensive rats. Arq Bras Cardiol. 2017; 108(6):539-45. 12. Lemos MP, Mota GRD, Marocolo M, Moura EOC, Medeiros A. Exercise training attenuates sympathetic activity and improves morphometry of splenic arterioles in spontaneously hipertensive rats. Arq Bras Cardiol. 2018;110(3):263-9. 13. Rodrigues AC, Natali AJ, Cunha DN, Costa AJ, Moura AG, Araujo Carneiro JR, M, et al. Moderate continuous aerobic exercise training improves cardiomyocyte contractility in β 1 adrenergic receptor knockout mice. Arq Bras Cardiol. 2018; 110(3):256-62. 14. Cai M, Wang Q, Liu Z, Jia D, Feng R, Tian Z. Effects of different types of exercise on skeletal muscle atrophy, antioxidant capacity and growth factors expression following myocardial infarction. Life Sci. 2018 Nov 15;213:40-9. 15. Ellingsen O, Halle M, Conraads V , Stevien A, dalin N, Delagardelle C, et al. SMARTEX Heart Failure Study (Study of Myocardial Recovery After Exercise Training in Heart Failure) Group. High-intensity interval training in patients with heart failurewith reduced ejection fraction. Circulation. 2017; 135(9):839-49. 16. Martinez JE, Taipeiro EF, Chies AB. Effects of continuous and accumulated exercise on endothelial function in rat aorta. Arq Bras Cardiol. 2017;108(4):315-22. References This is an open-access article distributed under the terms of the Creative Commons Attribution License Despite the great advances regarding the understanding of physical exercise effects on the healthy cardiovascular system or that submitted to different types of aggression, we are still far from clarifying the physical exercise mechanisms of action and from scientifically defining the best prescription for patients with cardiovascular disease. Acknowledgements We would like to thank Fundação de Amparo à Pesquisa do Estado de São Paulo – FAPESP (Proc. N. 2014/21972-3 and 2014/23592-3); Conselho Nacional de Desenvolvimento Científico e Tecnológico – CNPq (Proc. N. 310876/2018-4 and 153424/2018-4). 10