ABC | Volume 112, Nº6, June 2019

Original Article Carvalhal et al. Does GRACE Score modulate invasiveness? Arq Bras Cardiol. 2019; 112(6):721-726 Figure 1 – According to the area under the curve, GRACE Score does not predict an invasive strategy, as opposed to the propensity score (Panel A, p < 0.001 for curve comparison). Conversely, GRACE Score is better than the propensity Score for the prediction of mortality (Panel B, p < 0.001). 1.0 1.0 0.8 0.8 0.6 0.6 0.4 0.4 0.2 0.2 0.0 0.0 1.0 1.0 0.8 0.8 0.6 0.6 0.4 0.4 0.2 0.2 0.0 0.0 GRACE Propensity Score Reference Line GRACE Propensity Score Reference Line Sensitivity Sensitivity 1 – Specificity 1 – Specificity A B Invasive Prediction Death Prediction Table 1 – Exploratory analysis of variable associates with strategy Chosen Strategy p value Invasive Selective Sample Size 394 176 Male Gender 204 (52%) 82 (47%) 0.25* Age (years) 66 ± 14 69 ± 14 0.01† Positive Troponin 249 (63%) 69 (39%) < 0.001* ST Depression 94 (24%) 24 (14%) 0.005* Killip > 1 57 (15%) 24 (14%) 0.81* LV Ejection Fraction < 45% 26 (7.3%) 12 (7.8%) 0.84* Systolic BP (mmHg) 154 ± 28 155 ± 33 0.68† Heart Rate (bpm) 79 ± 20 77 ± 16 0.30† Creatinine (mg/dl) 1.1 ± 0.84 1.2 ± 1.1 0.35† Diabetes 143 (36%) 62 (35%) 0.79* Smoking 33 (8.4%) 11 (6.3%) 0.38* Number of Risk Factors 2.2 ± 1.0 2.1 ± 1.1 0.21† Known Coronary Artery Disease 209 (53%) 104 (59%) 0.19* Hemoglobin 13.4 ± 1.8 12.7 ± 2.1 < 0.001† CRUSADE Bleeding Score 38 ± 15 41 ± 14 0.02† Known Coronary Artery Disease =Definitive history of myocardial infarction or coronary obstruction ≥50% at angiography; LV: left ventricle. BP: blood pressure. *Pearson’s chi-square test p-values; † Unpaired Student’s T test p-values. 723