ABC | Volume 112, Nº6, June 2019

Original Article Ding et al The clinical significance of platelet parameters such as MPV Arq Bras Cardiol. 2019; 112(6):715-719 MPV has important significance in the evaluation of arterial thrombotic diseases such as cardiovascular thrombotic diseases. Therefore, MPV can act as an independent factor for the diagnosis and assessment of conditions and the curative effect of ACS. MPV levels in both the AMI and SCAD groups were significantly higher than normal levels, while PLT levels were significantly lower. These indicators are worthwhile in practice for disease diagnosis. In addition, based on the assessment of the diagnostic efficacy of the ROC curve for these parameters, the predicting value of MPV and PLT in AMI was superior to that in SCAD. In summary, the present study revealed that MPV- and PLT-related indicators are valuable for AMI and SCAD diagnostic prediction. However, there are two shortcomings of our study: one is that the study design is cross-sectional, because of the difficulty in keeping contact with these patients; the other is that there are only about 30 patients in the AMI and SCAD groups. There is no doubt that these two problems constitute limitations of our study. Further studies need to be carried out in a larger cohorts of patients with AMI and SCAD, with a more appropriate design to confirm its value as a diagnostic marker. Author contributions Conception and design of the research: Ding L, Hua F; acquisition of data: Ding L, Sun L, Wang F, Zhu L; analysis and interpretation of the data: Ding L, Sun L, Wang F, Zhu L, Zhang T; statistical analysis: Ding L, Sun L, Wang F, Zhang T, Hua F; writing of the manuscript: Ding L, Zhu L, Zhang T, Hua F; critical revision of the manuscript for intellectual content: Hua F. Supervision: Hua F. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Jinshan Hospital, Fudan University under protocol number 785. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 1. Tomey M, Mehran R. Dual antiplatelet therapy dilemmas: duration and choice of antiplatelets in acute coronary syndromes. Curr Cardiol Rep. 2013;15(10):405. 2. Tjia J, Allison J, Saczynski JS, Tisminetzky M, Givens JL, Lapane K ,et al. Encouraging trends in acutemyocardial infarction survival in the oldest old. Am J Med. 2013;126(9):798-804. 3. 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