ABC | Volume 112, Nº5, May 2019

Original Article Gonzaga et al Cardiac autonomic modulation in breast cancer Arq Bras Cardiol. 2019; 112(5):555-563 Table 5 – Correlation of heart rate variability indices with the metabolic variables blood glucose, triglycerides, and high-density lipoprotein with and without adjustments for age in women with breast cancer Blood Glucose Triglycerides HDL Without adjustment Adjusted (Age) Without adjustment Adjusted (Age) Without adjustment Adjusted (Age) β95% CI p β95% CI p β 95% CI p β95% CI p β95% CI p β95% CI p Mean RR ms -0.08 (-2.96; 2.79) 0.950 -0.23 (-3.08; 2.61) 0.86 -0.76 (-1.81; 0.29) 0.141 -0.75 (-1.78; 0.27) 0.135 -2.68 ( -10.25; 4.88) 0.454 -0.52 (-9.52; 8.47) 0,900 SDNN ms -0.06 (-0.34; 0.21) 0.609 -0.07 (-0.36; 0.22) 0.60 -0.09 (-0.19; -0.00) 0.045 -0.09 (-0.19; 0.00) 0.055 0.03 (-0.733; 0.79) 0.930 0.13 (-0.81; 1.07) 0,766 Mean HR ms -0.00 ( -0.28; 0.26) 0.943 -0.00 (-2.26; 0.27) 0.97 0.06 (-0.03; 0.16) 0.194 -0.81 (-2.18; 0.54) 0.189 0.26 ( -0.44; 0.98) 0.431 0.07 (-0.78; 0.92) 0,856 RMSSD ms -0.03 (-0.18; 0.10) 0.584 -0.03 (-0.19; 0.11) 0.58 -0.04 (-0.09; 0.01) 0.107 -0.04 (-0.09; 0.01) 0.123 0.01 (-0.38; 0.40) 0.958 0.04( -0.43; 0.53) 0,828 NN50 count -0.05 (-0.40; 0.29) 0.738 -0.05 (-0.42; 0.32) 0.76 -0.05 (-0.18; 0.08) 0.448 -0.18 (-0.19; 0.09) 0.466 0.08 (-0.86; 1.04) 0.844 -0.06 (-1.12; 1.24) 0,913 pNN50 % -0.00 (-0.04; 0.03) 0.738 -0.00 (-0.04; 0.03) 0.76 -0.00 (-0.01; 0.00) 0.448 -0.18 (-0.20; 0.01) 0.466 0.00 (-0.08; 0.10) 0.844 0.00 (-0.11; 0.12) 0,913 RR tri -0.01 (-0.08; 0.04) 0.563 -0.01 (-0.08; 0.05) 0.563 -0.02 (-0.04; -0.00) 0.037 -0.02 (-0.04; -0.00) 0.046 0.02 ( -0.12; 0.20) 0.769 0.04 (-0.17; 0.27) 0,634 TINN ms -0.29 (-1.48; 0.89) 0.599 -0.26 (-1.51; 0.97) 0.646 -0.18 (-0.65; 0.28) 0.397 -0.19 (-0.67; 0.29) 0.405 1.62 (-1.45; 4.70) 0.273 1.57 (-2.25; 5.39) 0,955 VLF ms 2 -1.7E-005 (0.00; 0.00) 0.882 -2.0E-00 (-0.00; 0.00) 0.868 -5.5E-005 (0.00; 0.00) 0.218 -5.5E-005 (0.00; 0.00) 0.239 0.00 (-0.00; 0.00) 0.577 0.00 (-0.00; 0.00) 0,642 LF ms 2 -1.21 (-6.41; 3.97) 0.619 -1.20 (-6.70; 4.29) 0.639 -1.48 (-3.37; 0.41) 0.114 -1.48 (-3.48; 0.51) 0.131 0.95 (-13.16; 15.07) 0.885 -0.81 (-16.72; 18.35) 0,920 HF ms 2 -0.62 (-2.11; 0.86) 0.381 -0.59 (-2.16; 0.96) 0.419 -0.53 (-1.05; -0.01) 0.045 -0.53 (-1.07; 0.00) 0.051 0.36 (-3.76; 4.49) 0.850 -0.14 (-5.23; 4.95) 0,951 LF/HF ms 2 -0.00 (-0.02; 0.00) 0.291 -0.00 (-0.02; 0.00) 0.334 -0.00 (-0.00; 0.01) 0.390 0.00 (-0.01; 0.01) 0.482 0.00 (-0.03; 0.05) 0.674 -0.00 (-0.05; 0.04) 0,945 SD1 ms -0.28 (-0.13; 0.07) 0.568 0.10 (-0.48; 0.70) 0.561 -0.03 (-0.06; 0.00) 0.095 -0.03 (-0.07; 0.00) 0.110 0.00 (-0.28; 0.28) 0.991 0.03 (-0.31; 0.38) 0,830 SD2 ms -0.09 (-0.48; 0.29) 0.604 -0.10 (-0.51; 0.30) 0.596 -0.13 (-0.27; -0.00) 0.044 -0.13 (-0.27; 0.00) 0.053 0.05 (-1.01; 1.11) 0.918 0.19 (-1.11; 1.50) 0,749 PCR: C reactive protein; SDNN: standard deviation of all normal RR intervals, expressed in milliseconds; HR: heart rate; RMSSD: square root of the mean of the squared differences between adjacent normal RR intervals; NN50: number of pairs of successive NNs that differ by more than 50 ms; pNN50: proportion of NN50 divided by total number of NNs; TINN: triangular interpolation of NN interval; VLF: very low frequency; LF: low frequency; HF: high frequency; RR tr: RR triangular; SD1: instantaneous variability of beat-to-beat variability; SD2: long-term standard deviation of continuous RR intervals index; ms: milliseconds. 561