ABC | Volume 112, Nº5, May 2019

Original Article Gomes et al Thermoregulation in hypertensive rats Arq Bras Cardiol. 2019; 112(5):534-542 Figure 3 – Work (W, A) and mechanical efficiency (ME, B) during the acute physical exercise protocol. Data expressed as mean ± SD; * p < 0.05: C-SHR vs. C-WIS; + p < 0.05: T-SHR vs. T-WIS. C-WIS: control Wistar, T-WIS: trained Wistar, C-SHR: control SHR, T-SHR: trained SHR. C-WIS T-WIS T-SHR C-SHR C-WIS T-WIS T-SHR C-SHR 8000 6000 4000 2000 0 0 10 20 30 40 50 W (J) ME (%) A B + * al. 8 demonstrated that differences in the thermoregulation between normotensive animals and SHR during acute exercise were not dependent on variations of body mass. These differences could also affect the ability of the animals to be trained, since they could be associated with differences in body composition, and consequently in differences in physical capacity. Finally, we cannot affirm that the results would have been the same if physical training had been started before a SBP higher than 150 mmHg was achieved by the SHR, or if animals of different ages were studied. Conclusion Low-intensity physical training did not affect thermal balance in hypertensive rats subjected to an acute exercise protocol. Author contributions Conception and design of the research: Gomes LHLS, Natali AJ, Prímola-Gomes TN; Acquisition of data: Gomes LHLS, Rezende LMT, Prímola-Gomes TN; Analysis and interpretation of the data and critical revision of the manuscript for intellectual content: Gomes LHLS, Drummond LR, Campos HO, Rezende LMT, Carneiro-Júnior MA, Oliveira A, Natali AJ, Prímola‑Gomes TN; Statistical analysis: Gomes LHLS, Drummond LR, Campos HO, Rezende LMT, Oliveira A, Prímola-Gomes TN; Obtaining financing: Prímola-Gomes TN; Writing of the manuscript: Gomes LHLS, Drummond LR, Campos HO, Carneiro-Júnior MA, Prímola-Gomes TN. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was funded by FAPEMIG, CNPq and CAPES. Study Association This article is part of the thesis of master submitted by Luis Henrique Lobo Silame Gomes, from Universidade Federal de Viçosa. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Universidade Federal de Viçosa under the protocol number 76/2014. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 539