ABC | Volume 112, Nº5, May 2019

Viewpoint Souza et al. Resident macrophages and heart rate Arq Bras Cardiol. 2019; 112(5):588-591 Figure 1 – The normal condition of macrophage-cardiomyocyte couplings. Communications between cardiomyocytes and macrophages through connexin-43 (A) promoting normal cardiac rhythm (B). Figure 2 – Reduction in the expression of connexins. The coupling between macrophages and cardiomyocytes is decreased due to the reduction of connexin-43 (A) expression promoting electrical conduction pathologies (atrioventricular block of 3º degree - B). 589