ABC | Volume 112, Nº4, April 2019

Short Editorial Malachias Polycystic ovary syndrome and the heart Arq Bras Cardiol. 2019; 112(4):430-431 1. Philbois SV, Gastaldi AC, Facioli TP, Felix ACS, Reis RM, Fares TH, et al. Women with polycystic ovarian syndrome exhibit reduced baroreflex sensitivity that may be associated with increased body fat. Arq Bras Cardiol. 2019; 112(4):424-429. 2. Yau TT , Ng NY , Cheung LP , Ma RC . Polycystic ovary syndrome: a common reproductivesyndromewith long-termmetabolicconsequences. HongKong Med J. 2017;23(6):622-34. 3. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab. 2004;89(6):2745-9. 4. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, et al. The androgen excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2009;91(2):456-88. 5. Sartor BM, Dickey RP. Polycystic ovarian syndrome and the metabolic syndrome. Am J Med Sci. 2005;330(6):336-42. 6. Colilla S, Cox NJ, Ehrmann DA. Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives. J Clin Endocrinol Metab. 2001;86(5):2027-31. 7. LegroRS,GnatukCL,KunselmanAR,DunaifA.Changes inglucosetolerance over time in women with polycystic ovary syndrome: a controlled study. J Clin Endocrinol Metab. 2005;90(6):3236-42. 8. Boudreaux MY, Talbott EO, Kip KE, Brooks MM, Witchel SF. Risk of T2DM and impaired fasting glucose among PCOS subjects: results of an 8-year follow-up. Curr Diab Rep. 2006;6(1):77-83. 9. Vgontzas AN, Legro RS, Bixler EO, Grayev A, Kales A, Chrousos GP. Polycystic ovary syndrome is associated with obstructive sleep apnea and daytime sleepiness: role of insulin resistance. J Clin Endocrinol Metab. 2001;86(2):517-20. 10. Gopal M, Duntley S, UhlesM, AttarianH. The role of obesity in the increased prevalence of obstructive sleep apnea syndrome in patients with polycystic ovarian syndrome. Sleep Med. 2002;3(5):401-4. 11. Luque-RamirezM, Mendieta-Azcona C, Alvarez-Blasco F, Escobar-Morreale HF. Androgen excess is associated with the increased carotid intima-media thickness observed in young women with polycystic ovary syndrome. Hum Reprod. 2007;22(12):3197-203. 12. Talbott EO, Zborowski JV, Rager JR, Boudreaux MY, Edmundowicz DA, Guzick DS. Evidence for an association between metabolic cardiovascular syndrome and coronary and aortic calcification among women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2004;89(11):5454-61. 13. Boulman N, Levy Y, Leiba R, Shachar S, Linn R, Zinder O, et al. Increased C-reactive protein levels in the polycystic ovary syndrome: a marker of cardiovascular disease. J Clin Endocrinol Metab. 2004;89(5):2160-5. 14. Aguado LI. Role of the central and peripheral nervous system in the ovarian function. J Microsc Res Tech. 2002;59(6):462-73. 15. Sverrisdottir YB, Mogren T, Kataoka J, Janson PO, Stener-Victorin E. Is polycystic ovary syndrome associated with high sympathetic nerve activity and size at birth? Am J Physiol Endocrinol Metab. 2008;294(3):E576-81. 16. Tsuji H, Larson MG, Venditti Jr FJ, Manders ES, Evans JC, Feldman CL, et al. Impact of reduced heart rate variability on risk for cardiac events. The FraminghamHeart Study. Circulation. 1996;94(11):2850-5. 17. Lara HE, Ferruz JL, Luza S, Bustamante DA, Borges Y, Ojeda SR. Activation of ovarian sympathetic nerves in polycystic ovary syndrome. Endocrinology. 1993;133(6):2690-5. 18. Yildirir A, Aybar F, Kabakci G, Yarali H, Oto A. Heart rate variability in young women with polycystic ovary syndrome. Ann Noninvasive Electrocardiol. 2006;11(4):306-12. 19. TekinG, Tekin A, Kilicarslan EB, Haydardedeoglu B, Katircibasi T, KocumT, et al. Altered autonomic neural control of the cardiovascular system in patients with polycystic ovary syndrome. Int J Cardiol. 2008;130(1):49-55. 20. Dag ZO, Alpua M, Turkel Y, Isik Y Autonomic dysfunction in patients with polycystic ovary syndrome. Taiwan J Obstet Gynecol. 2015;54(4):381-4. 21. Di Domenico K, Wiltgen D, Nickel FJ, Magalhães JA, Moraes RS, Spritzer PM. Cardiac autonomicmodulation in polycystic ovary syndrome: does the phenotype matter? Fertil Steril. 2013;99(1):286-92. 22. Thayer JF, Yamamoto SS, Brosschot JF. The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors. Int J Cardiol. 2010;141(2):122-31. 23. Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E, et al. American Association Of Clinical Endocrinologists, American College Of Endocrinology, and Androgen Excess and Pcos Society Disease State Clinical Review: guide to the best practices in the evaluation and treatment of Polycystic Ovary Syndrome - part 2. Endocr Pract. 2015;21(12):1415-26. References This is an open-access article distributed under the terms of the Creative Commons Attribution License 431

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