ABC | Volume 112, Nº4, April 2019

Short Editorial Rodrigues Inflammatory score in resistant hypertension Arq Bras Cardiol. 2019; 112(4):390-391 1. Carey RM, Calhoun DA, Bakris GL, Brook RD, Daugherty SL Dennison- Himmelfarb CR, et al. Resistant hypertension: detection, evaluation, and management: a scientific statement from the American Heart Association. Hypertension. 2018;72(5):e53-90. 2. AlessiA,BrandãoAA,CocaA,CordeiroAC,NogueiraAR,FeitosaAM,etal..First brazilianpositiononresistanthypertension.ArqBrasCardiol.2012;99(1):576-85. 3. Daugherty SL, Powers JD, Magid DJ, Tavel HM, Masoudi FA, Margolis KL, et al. Incidence and prognosis of resistant hypertension in hypertensive patients. Circulation. 2012;125(13):1635-42. 4. Muxfeldt ES, Chedier B, Rodrigues CIS. Resistant and refractory hypertension: two sides of the same disease? J Bras Nefrol. 2018 Dec 6. Pii:S0101- 28002018005045101. 5. Sheppard JP,MartinU,MacManusRJ.Diagnosisandmanagementofresistant hypertension. Heart. 2017;103(16):1295-302. 6. de la Sierra A, Larrousse M. Endothelial dysfunction is associated with increased levels of biomarkers in essential hypertension. J HumHypertens. 2010;24(6):373-9. 7. Shere A, Eletta O, Goyal H. Circulating blood biomarkers in essential hypertension: a literature review. J Lab Precis Med. 2017;2:99. 8. StrimbuK,TavelJA.Whatarebiomarkers?CurrOpinHIVAIDS.2010;5(6):463-6. 9. Junqueira CLC, Magalhães MEC, Brandão AA, Ferreira E, Cyrino FZGA, Maranhão PA, et al. Microcirculation and biomarkers in patients with resistant or mild-to-moderate hypertension: a cross-sectional study. Hypertens Res. 2018;41(7):515-23. 10. de Faria APC, Ritter AMV, Gasparetti CS, et al. Proposta de um Escore Inflamatório de Citocinas e Adipocinas Plasmáticas Associado à Hipertensão Resistente, mas Dependente de Parâmetros de Obesidade. Arq Bras Cardiol. 2019; 112(4):383-389. 11. Chaudhary K, Buddinemi JP, Nistala R Whaley-Connell A.. Resistant hypertension in the high-risk metabolic patient. Curr Diab Rep. 2011;11(1):41-6. 12. DeMarco VG, Arooor AR, Sowers JR. The pathophysiology of hypertension in patients with obesity. Nat Rev Endocrinol. 2014;10(6):364-76. References This is an open-access article distributed under the terms of the Creative Commons Attribution License Therefore, it is expected we can better understand the pathophysiology of resistant hypertension in the presence of obesity and the biological phenomena that culminate in oxidative stress, inflammation and endothelial microvascular dysfunction. The study published in this issue contributes qualitatively to this understanding. 391