ABC | Volume 112, Nº4, April 2019

Original Article de Faria et al Inflammatory score and resistant hypertension Arq Bras Cardiol. 2019; 112(4):383-389 This is an open-access article distributed under the terms of the Creative Commons Attribution License 25. Daniele G, Guardado Mendoza R, Winnier D, Fiorentino TV, Pengou Z, Cornell J, et al. The inflammatory status score including IL-6, TNF-alpha, osteopontin, fractalkine, MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus. Acta Diabetol. 2014;51(1):123-31. 26. Esposito K, Pontillo A, Di Palo C, Giugliano G, Masella M, Marfella R, et al. Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA. 2003;289(14):1799-804. 27. Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, et al. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance . Obes Res. 2003;11(9):1048-54. 28. Scalia, R. The microcirculation in adipose tissue inflammation. Rev Endocr Metab Disord. 2013;14(1):69-76. 29. BakkerW,SipkemaP,StehouwerCD,SerneEH,SmuldersYM,vanHinsbergh VW, et al. Protein kinase C theta activation induces insulin-mediated constriction of muscle resistance arteries . Diabetes. 2008;57(3):706-13. 30. Yudkin JS, Eringa E, Stehouwer CD. “Vasocrine” signalling fromperivascular fat: a mechanism linking insulin resistance to vascular disease. Lancet. 2005;365(9473):1817-20. 31. Rossi M, Nannipieri M, AnselminoM, PesceM, Muscelli E, Santoro G, et al. Skin vasodilator function and vasomotion in patients with morbid obesity: effects of gastric bypass surgery . Obes Surg. 2011;21(1):87-94. 32. Vincent MA, Montagnani M, Quon MJ. Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium . Curr Diab Rep. 2003;3(4):279-88. 33. Landmesser U, Drexler H. Endothelial function and hypertension.Curr Opin Cardiol. 2007;22(4):316-20. 34. Perticone F, Ceravolo R, Pujia A, Ventura G, Iacopino S, Scozzafava A, et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation. 2001;104(2):191-6. 35. Koh KK, Son JW, Ahn JY, Jin DK, Kim HS, Choi YM, et al. Comparative effects of diet and statin on NO bioactivity and matrix metalloproteinases in hypercholesterolemic patients with coronary artery disease. Arterioscler Thromb Vasc Biol. 2002;22(9):e19-23. 36. Koh KK, Schenke WH, Waclawiw MA, Csako G, Cannon RO 3rd. Statin attenuates increase in C-reactive protein during estrogen replacement therapy in postmenopausal women. Circulation. 2002;105(13):1531-3. 37. Koh KK, Ahn JY, Han SH, KimDS, JinDK, KimHS, et al. Pleiotropic effects of angiotensin II receptor blocker in hypertensive patients . J Am Coll Cardiol. 2003;42(5):905-10. 38. Trevelyan J, Brull DJ, Needham EW, Montgomery HE, Morris A, Mattu RK. Effect of enalapril and losartan on cytokines in patients with stable angina pectoris awaiting coronary artery bypass grafting and their interaction with polymorphisms in the interleukin-6 gene. Am J Cardiol. 2004;94(5):564-9. 39. GuoC,RicchiutiV,LianBQ,YaoTM,CoutinhoP,RomeroJR,etal.Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisomeproliferator-activatedreceptor-gamma,andproinflammatoryadipokines. Circulation.2008;117(17):2253-61. 40. TrøseidM, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, et al. Exercise reduces plasma levels of the chemokinesMCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J. 2004;25(4):349-55. 41. Hu P, Thinschmidt JS, Yan Y, Hazra S, Bhatwadekar A, Caballero S, et al. CNS inflammation and bonemarrowneuropathy in type 1 diabetes. Am J Pathol. 2013;183(5):1608-20. 42. Santisteban MM, Ahmari N, Carvajal JM, Zingler MB, Qi Y, Kim S, et al. Involvement of bonemarrow cells and neuroinflammation in hypertension . Circ Res. 2015;117(2):178-91. 43. LiuW, Wang X, FengW, Li S, TianW, Xu T, et al. Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats. Exp Mol Pathol. 2011;91(1):362-7. 389

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