ABC | Volume 112, Nº3, March 2019

Original Article Castro et al Troponin I after acute coronary syndrome Arq Bras Cardiol. 2019; 112(3):230-237 Figure 2 – Kaplan-Meier curve for cardiovascular mortality according to hs-cTnI tertile measured 25 to 90 days after acute coronary syndrome. 1.0 0.8 0.6 0.4 0.2 0.0 0 500 1000 1500 2500 2000 Time (days) Probability of survival p < 0.001 by the Log-rank test 1st tertile 2nd tertile 3rd tertile 1st tertile 179 173 162 109 33 3 2nd tertile 171 157 147 98 39 5 3rd tertile 175 149 131 90 43 5 Numbers at risk Table 2 – Hazard ratios and respective 95% confidence intervals on crude and age-sex adjusted models, and two multivariate adjusted models of Cox regression analysis Crude Age-sex adjusted Multivariate adjusted (Model 1) Multivariate adjusted (Model 2) All-cause mortality 1 st tertile (reference) 1.0 (reference) 1.0 (reference) 1.0 (reference) 2 nd tertile 2.44 (1.23-4.81) 2.02 (1.02-4.01) 1.86 (0.86-4.05) 2.33 (0.74-7.33) 3 rd tertile 4.20 (2.22-7.94) 4.14 (2.19-7.86) 3.84 (1.92-8.12) 6.53 (2.12-20.14) Cardiovascular mortality 1 st tertile (reference) 1.0 (reference) 1.0 (reference) 1.0 (reference) 2 nd tertile 3.77 (1.24-11.47) 2.90 (0.95-8.90) 2.66 (0.72-9.84) 1.30 (0.21-8.00) 3 rd tertile 6.05 (2.08-17.57) 5.65 (1.94-16.47) 4.90 (1.35-17.82) 5.89 (1.08-32.27) Model 1: Adjusted for age, sex, ACS subtype, hypertension, diabetes, dyslipidemia, smoking history, body mass index, and medication use at first follow-up (25–90 days after ACS). Model 2: Model 1 with addition of estimated GFR < 60 ml/min/1.73 m 2 and LVEF < 0.40. revision of the manuscript for intellectual content: Castro LT, Santos IS, Goulart AC, Pereira AC, Staniak HL, Bittencourt MS, Lotufo PA, Bensenor IM. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the Doctoral thesis submitted by Leandro Teixeira de Castro, from Universidade de São Paulo. 235