ABC | Volume 112, Nº3, March 2019

Brief Communication Ribeiro et al Beta-blocker effect on substrate oxidation during exercise in heart failure Arq Bras Cardiol. 2019; 112(3):304-308 Figure 1 – A) Carbohydrate oxidation by group at rest and 8-10 minutes high-intensity interval exercise. B) Lipids oxidation by groups at rest and 8-10 minutes high- intensity interval exercise. *p < 0.05 for groups; ANOVA p value results: A: group; B: time; C: interaction. A: p = 0.012 B: p = < 0.001 C: p = 0.029 25 22.5 17.5 12.5 7.5 2.5 0 20 15 10 5 Rest 8-10 min – Exercise Meto+Biso Carvedilol * A CHO oxydation (mg/min*kg –1 ) A: p = 0.017 B: p = 0.005 C: p = 0.122 4 3.5 2.5 1.5 0.5 0 3 2 1 Rest 8-10 min – Exercise Meto+Biso Carvedilol * * B Lipids oxydation (mg/min*kg –1 ) Sources of Funding This study was funded by the ÉPIC Fondation, the Montreal Heart Institute Foundation and the CNPq. Study Association This article is part of the Post-Doctoral fellowship submitted by Paula Aver Bretanha Ribeiro, from University of Montreal. 307