ABC | Volume 112, Nº1, January 2019

Original Article Enhos et al Atherosclerosis and MB Arq Bras Cardiol. 2019; 112(1):12-17 1. Bourassa MG, Butnaru A, Lespérance J, Tardif JC. Symptomatic myocardial bridges: Overview of ischemic mechanisms and current diagnostic and treatment strategies. J Am Coll Cardiol. 2003;41(3):351-9. 2. Reyman HC. Disertatio de vasis cordis propriis [dissertation]. Gottingen: Med Diss Univ; 1737. 3. Portmann W, Iwig J. Die intramurale koronarie im angiogramm. Fortschr Rontgenstr 1960;92(2):129-133. 4. BautersC,ChmaitA,TricotO,LamblinN,VanBelleE,LablancheJM.Coronary thrombosis andmyocardial bridging. Circulation. 2002;105(1):130. 5. Rossi L, Dander B, Nidasio GP, Arbustini E, Paris B, Vassanelli C, et al. Myocardialbridgesandischemicheartdisease.EurHeartJ.1980;1(4):239-45. 6. Schwarz ER, Klues HG, VomDahl J, Klein I, Krebs W, Hanrath P. Functional, angiographic and intracoronaryDoppler flow characteristicsin symptomatic patients with myocardial bridging: effect ofshort-term intravenous beta- blocker medication. J Am Coll Cardiol. 1996;27(7):1637-45. 7. Ge J, Erbel R, Rupprecht HJ, Koch L, Kearney P, Gorge G, et al. Comparison of intravascular ultrasound and angiography in the assessment of myocardial bridging. Circulation. 1994;89(4):1725-32. 8. Kneale BJ, Stewart AJ, Coltart DJ. A case of myocardial bridging: evaluation using intracoronary ultrasound, Doppler flow measurement, and quantitative coronary angiography. Heart. 1996;76(4):374-6. 9. Libby P. Inflammation in atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32(9):2045-51. 10. CanpolatU,ÇetinEH,CetinS,AydinS,AkbogaMK,YaylaC,etal. Association of Monocyte-to-HDL cholesterol ratio with slow coronary flow is linked to systemic inflammation. Clin Appl Thromb Hemost. 2016;22(5):476-82. 11. Cockerill GW, Rye KA, Gamble JR, Vadas MA, Barter PJ. High-density lipoproteins inhibit cytokine-induced expression of endothelial, cell adhesionmolecules. Arterioscler Thromb Vasc Biol. 1995;15(11):1987-94. 12. Mohlenkamp S, Hort W, Ge J, Erbel R. Update on myocardial bridging. Circulation. 2002;106(20):2616-22. 13. Ishikawa Y, Ishii T, Asuwa N, Masuda S. Absence of atherosclerosis evolution in the coronary arterial segment covered bymyocardial tissue in cholesterol- fed rabbits. Virchows Arch. 1997;430(2):163-71. 14. IshiiT,HosodaY,OsakaT, ImaiT,ShimadaH,TakamiA,etal.Thesignificance of myocardial bridge upon atherosclerosis in the left anterior descending coronary artery. J Pathol. 1986;148(4):279-91. References Table 3 – Multivariate analysis to detect independent variables for the diagnosis of myocardial bridge Variables Odds ratio Confidence İnterval(%95) p-value Age 1.010 0.979 – 1.041 0.540 Gender 1.273 0.463 – 3.494 0.640 Total cholesterol 0.995 0.986 – 1.004 0.288 MHR 1.128 1.055 – 1.207 < 0.001 NLR 1.012 0.750 – 1.367 0.936 Hemoglobin 1.145 0.896 – 1.463 0.278 MHR: Mononcyte count/HDL cholesterol ratio; NLR: neutrophil / lymphocyte ratio. determined due to a lack of follow-up of the study patients. Moreover, the effect of other inflamatory markers, like C-reactive protein, was not assesed due to a lack of records. Conclusions In conclusion, since increased MHR is a marker of inflammation and atheroclerosis, MB could be one of the factors associated with increased MHR. Author contributions Conception and design of the research: Enhos A, Bakshaliyev N; acquisition of data: Enhos A, Cosansu K, Huyut MA, Bakshaliyev N, Nadir A; analysis and interpretation of the data: Enhos A, Cosansu K, Huyut MA; statistical analysis: Turna F; obtaining funding: Enhos A, Cosansu K, Turna F, Karacop E, Nadir A; writing of the manuscript and critical revision of the manuscript for intellectual content: Enhos A, Karacop E, Ozdemir R, Uluganyan M. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Bezmialem Vakif Universty under the protocol number 342018. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 16