ABC | Volume 111, Nº5, November 2018

Original Article Lima et al High-intensity interval training and heart failure Arq Bras Cardiol. 2018; 111(5):699-707 Figure 3 – Variation of blood pressure pre- and post-high-intensity interval training session. Data are expressed as mean± standard deviation. Lines represent mean values:.1) pre-assessment of endothelial function; 2) immediately before HIIT session; 3) 5 minutes after HIIT session; 4) 30 minutes after HIIT session. SBP, systolic blood pressure; MBP, mean blood pressure; DBP, diastolic blood pressure. Probability value indicates within-group differences between points 3 and 1, and points 4 and 1 of SBP. *p < 0.05, **p < 0.01. 160 150 140 130 120 110 100 90 80 70 60 1 2 3 4 SBP MBP DBP * ** Blood pressure (mmHg) 1. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction.N Engl J Med. 2006;355(3):251-9. 2. Redfield MM. Heart failure with preserved ejection fraction. N Engl J Med. 2016;375(19):1868-77. 3. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012;33(14):1787-847. 4. McMurray JJ, Carson PE, Komajda M, McKelvie R, Zile MR, Ptaszynska A, et al. Heart failure with preserved ejection fraction: clinical characteristics of 4133 patients enrolled in the I-PRESERVE trial. Eur J Heart Fail. 2008;10(2):149–56. 5. WRITING COMMITTEE MEMBERS, Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE Jr, Drazner MH,et al. 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;128(16): e240–e327. 6. Paulus WJ, Tschöpe C. A novel paradigm for heart failure with preserved ejection fraction. J Am Coll Cardiol. 2013;62(4):263–71. 7. Lim SL, Lam SPC. Breakthrough in heart failure with preserved ejection fraction: are we there yet? Korean J Intern Med. 2016;31(1):1-14. 8. Haykowsky MJ, Kitzman DW. Exercise physiology in heart failure and preserved ejection fraction. Heart Fail Clin. 2014;10(3):445–52. 9. Borlaug BA, Olson TP, LamCS, Flood KS, LermanA, Johnson BD, et al. Global cardiovascular reserve dysfunction in heart failure with preserved ejection fraction. J Am Coll Cardiol. 2010;56(11):845-54. 10. BorlaugBA,MelenovskyV,RussellSD,KesslerK,PacakK,BeckerLC,etal.Impaired chronotropicandvasodilatorreserveslimitexercisecapacityinpatientswithheart failureandapreservedejectionfraction.Circulation.2006;114(20):2138–47. 11. Akiyama E, Sugiyama S, Matsuzawa Y, Konishi M, Suzuki H, Nozaki T, et al. Incremental prognostic significance of peripheral endothelial dysfunction in patients with heart failure with normal left ventricular ejection fraction. J Am Coll Cardiol.2012;60(18):1778–86. 12. Matsue Y, Suzuki M, NagahoriW, OhnoM,Matsumura A, Hashimoto Y, et al. Endothelial dysfunctionmeasured by peripheral arterial tonometry predicts prognosis in patients with heart failure with preserved ejection fraction. Int J Cardiol .2013;168(1):36-40. 13. Pandey A, Parashar A, Kumbhani JD, Agarwal S, Garg J, Kitzman D, et al. Exercise training in patients with heart failure and preserved ejection fraction: meta-analysis of randomized control trials. Circ Heart Fail. 2015;8(1):33–40. 14. Dieberg G, Ismail H, Giallauria F, Smart NA. Clinical outcomes and cardiovascular responses to exercise training in heart failure patients with preserved ejection fraction: a systematic review and meta-analysis. J Appl Physiol. 2015;119(6):726–33. 15. Mezzani A, Hamm LF, Jones AM, McBride PE, Moholdt T, Stone JA, et al. Aerobicexerciseintensityassessmentandprescriptionincardiacrehabilitation: a JOINT POSITION STATEMENT OF THE EUROPEAN ASSOCIATION FOR CARDIOVASCULAR PREVENTION AND REHABILITATION, THE AMERICAN ASSOCIATION OF CARDIOVASCULAR AND PULMONARY REHABILITATION, AND THE CANADIAN ASSOCIATION OF CARDIAC REHABILITATION. J CardiopulmRehabil Prev. 2012;32(6):327–50. 16. Wisløff U, Støylen A, Loennechen JP, BruvoldM, Rognmo Ø, Haram PM, et al. Superior cardiovascular effect of aerobic interval training versusmoderate continuous training in heart failure patients: a randomized study. Circulation .2007;115(24):3086–94. References Ethics approval and consent to participate This study was approved by the Ethics Committee of the Hospital Clínicas de Porto Alegre under the protocol number 130471. All the procedures in this study were in accordance with the1975Helsinki Declaration, updated in2013. Informed consent was obtained from all participants included in the study. 705