ABC | Volume 111, Nº5, November 2018

Counterpoint Izar Flexibilization of fasting: science or convenience Arq Bras Cardiol. 2018; 111(5):750-752 This is an open-access article distributed under the terms of the Creative Commons Attribution License initiative. Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points-a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine. Eur Heart J. 2016;37(25):1944-58. 8. ChapmanMJ, Ginsberg HN, Amarenco P, Andreotti F, Boren J, Catapano AL, et al; European Atherosclerosis Society Consensus Panel. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J. 2011;32(11):1345-61. 9. Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, et al; AmericanHeart AssociationClinical Lipidology, Thrombosis, and Prevention Committee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Nursing; Council on the Kidney in Cardiovascular Disease. Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2011;123(20):2292-333. 10. TannoK,OkamuraT,OhsawaM,OnodaT, ItaiK,SakataK,etal.Comparison of low-density lipoprotein cholesterol con- centrations measured by a direct homogeneous assay and by the Friedewald for- mula in a large community population. Clin Chim Acta. 2010;411(21-22):1774-80. 11. Mora S, Rifai N, Buring JE, Ridker PM. Comparison of LDL cholesterol concentra-tionsbyFriedewaldcalculationanddirectmeasurement inrelation to cardiovascular events in 27,331 women. Clin Chem. 2009;55(5):888-94. 12. Mihaylova B, Emberson J, Blackwell L, Keech A, Simes J, Barnes EH, et al; Cholesterol Treatment Trialists’ (CTT) Collaborators. The effect of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 2012;380(9841):581-90. 13. Boekholdt SM, Arsenault BJ, Mora S, Pedersen TR, LaRosa JC, Nestel PJ, et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins. JAMA. 2012;307(12):1302-9. Erratum in: JAMA. 2012;307(18):1915. JAMA. 2012;307(16):1694. 14. Langsted A, Freiberg JJ, Nordestgaard BG. Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction. Circulation. 2008;118(20):2047-56. 15. Langsted A, Kamstrup PR, Nordestgaard BG. Lipoprotein(a): fasting and nonfasting levels, inflammation, and cardiovascular risk. Atherosclerosis. 2014;234(1):95-101. 16. Mora S, Rifai N, Buring JE, Ridker PM. Fasting compared with nonfasting lipids and apolipoproteins for predicting incident cardiovascular events. Circulation. 2008;118(10):993-1001. 17. Sidhu D, Naugler C. Fasting time and lipid levels in a community-based population:across-sectionalstudy.ArchInternMed .2012;172(22):1707-10. 18. Steiner MJ, Skinner AC, Perrin EM. Fasting might not be necessary before lipid screening: a nationally representative cross-sectional study. Pediatrics. 2011;128(3):463-70. 19. Langsted A, Nordestgaard BG. Nonfasting lipids, lipoproteins, and apolipoproteins in individuals with and without diabetes: 58,434 individuals from the Copenhagen General Population Study. Clin Chem. 2011;57(3):482-9. 20. Simundic AM, Cornes M, Grankvist K, Lippi G, Nybo M. Standardization of collection requirements for fasting samples: for the Working Group on Preanalytical Phase (WG-PA) of the European Federation of Clinical Chemis- tryandLaboratoryMedicine(EFLM).ClinChimActa.2014May15;432:33-7. 21. Martin SS, BlahaMJ, ElshazlyMB, Toth PP, Kwiterovich PO, Blumenthal RS, et al. Comparison of a novel method vs the Friedewald equation for estimating low-density lipoprotein cholesterol levels from the standard lipid profile. JAMA. 2013;310(19):2061-8. 22. Scartezini M, Ferreira CE, Izar MC, Bertoluci M, Vencio S, Campana GA, et al. Positioning about the flexibility of fasting for lipid profiling. Arq Bras Cardiol. 2017;108(3):195-7. 752