ABC | Volume 111, Nº3, September 2018

Original Article Nemes et al RA function in CA by 3DSTE Arq Bras Cardiol. 2018; 111(3):384-391 Figure 1 – Images from three-dimensional (3D) full-volume dataset showing the right atrium (RA) are presented: apical four-chamber (A) and two-chamber views (B) and short-axis views at basal (C3), mid- (C5) and superior (C7) RA levels together with a virtual 3D model of the RA (red D) and with RA volumetric data (red E). Time – segmental (longitudinal) strain curves of all 16 RA segments (coloured lines) and a time - global RA volume change curve respecting cardiac cycle (white dashed line) are also presented (red F). Yellow arrow represents peak RAstrain, while yellow dashed arrow represents RAstrain at atrial contraction. V max , V min and V preA represent maximum and minimum RA volumes and RA volume at atrial contraction, respectively. LV: left ventricle; LA: left atrium; RV: right ventricle; RA: right atrium. Table 1 – Baseline demographic and two-dimensional echocardiographic data in patients with cardiac amyloidosis and matched controls AL-CA patients (n = 16) Controls (n = 15) p-value Risk factors Age (years) 64.5 ± 10.1 58.9 ± 6.9 0.08 * Male gender (%) 11 (69) 8 (53) 0.47 ** Hypertension (%) 11 (69) 0 (0) < 0.0001 ** Diabetes mellitus (%) 1 (6) 0 (0) 0.46 ** Hypercholesterolaemia (%) 6 (38) 0 (0) 0.02 ** Two-dimensional echocardiography LA diameter (mm) 45.1 ± 6.7 36.6 ± 4.00 < 0.0001 * LV end-diastolic diameter (mm) 47.1 ± 5.7 47.3 ± 3.2 0.93 * LV end-diastolic volume (ml) 112.9 ± 31.9 104.9 ± 16.7 0.42 * LV end-systolic diameter (mm) 30.0 ± 5.3 30.4 ± 2.8 0.80 * LV end-systolic volume (ml) 41.7 ± 15.4 35.7 ± 6.9 0.11 * Interventricular septum (mm) 14.2 ± 1.9 10.4 ± 1.7 < 0.0001 * LV posterior wall (mm) 13.6 ± 1.7 10.4 ± 1.9 0.0003 * LV ejection fraction (%) 61.5 ± 11.9 65.7 ± 4.8 0.21 * E/A 1.71 ± 1.08 1.00 ± 0.45 0.14 * CA: cardiac amyloidosis; LA: left atrial; LV: left ventricular. Data expressed as mean ± standard deviation or or absolute numbers (percentage). * Unpaired Student t test, ** χ 2 test. 386

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