ABC | Volume 111, Nº3, September 2018

Original Article Kanar et al RV function after pulmonary rehabilitation program Arq Bras Cardiol. 2018; 111(3):375-381 Table 1 – Clinical, conventional echocardiographic, and ventricular strain data in patients undergoing pulmonary rehabilitation and in healthy control subjects Patients undergoing pulmonary rehabilitation (n: 46) Healthy control subjects (n: 32) p value Age (years) 60.8 ± 10.2 58.5 ± 8.9 0.15 Gender (male,%) 28(61%) 13(41%) Body mass index (kg/m 2 ) 28.2 ± 8.4 27.9 ± 7.2 0.67 Heart rate (beats/min) 78 ± 12 80 ± 10 0.77 GOLD classes 2/3/4, n 22/18/7 RV end-diastolic basal diameter (mm) 38.1 ± 4.1 27.6 ± 3.5 < 0.001 RV end-diastolic longitudinal diameter (mm) 74.2 ± 9.4 60.4 ± 6.4 < 0.001 RV anterior wall thickness (mm) 4.35 ± 0.21 4.19 ± 0.31 0.82 RA end-systolic area (mm 2 ) 17.2 ± 2.9 12.9 ± 1.8 < 0.001 sPAB (mmHg) 46.7 ± 15.4 24.8 ± 10.5 < 0.001 TAPSE (mm) 16.6 ± 2.6 20.4 ± 3.1 < 0.001 Tissue Doppler MPI 0.58 ± 0.08 0.35 ± 0.05 < 0.001 RV ejection fraction (%) 54.8 ± 4.9 56.3 ± 5.5 0.41 LV ejection fraction (%) 57.7 ± 5.5 59.4 ± 4.4 0.34 RV-TDI s' 12.9 ± 2.93 13.6 ± 3.06 0.38 RV free wall longitudinal strain (%) 18.1 ± 3.4 27.9 ± 3.6 < 0.001 RV global longitudinal strain (%) 20.4 ± 2.4 26.8 ± 3.2 < 0.001 Data are presented as mean ± standard deviation or percentile. Bold values indicate statistical significance p < 0.05. GOLD: global initiative for chronic obstructive lung disease; RV: right ventricle; RA: right atrium; sPAP: systolic pulmonary artery pressure; TAPSE: tricuspid annular plane systolic excursion; TDI s’: tissue Doppler imaging systolic excursion; MPI: myocardial performance index; LV: left ventricle. Table 2 – Standard echocardiographic and ventricular strain data in patients before and after pulmonary rehabilitation Before pulmonary rehabilitation (n:46) 3 months after pulmonary rehabilitation (n:46) p value RV end-diastolic basal diameter (mm) 38.1 ± 4.1 37.7 ± 4.0 0.23 RV end-diastolic longitudinal diameter (mm) 74.2 ± 9.4 73.5 ± 9.3 0.69 RV anterior wall thickness (mm) 4.35 ± 0.21 4.22 ± 0.26 0.87 RA end-systolic area (mm 2 ) 17.2 ± 2.9 16.9 ± 2.4 0.18 sPAB (mmHg) 46.7 ± 15.4 43.2 ± 16.3 0.03 TAPSE (mm) 16.6 ± 2.6 17.2 ± 3.1 0.09 Tissue Doppler MPI 0.58 ± 0.08 0.55 ± 0.07 0.09 RV ejection fraction (%) 54.8 ± 4.9 55.2 ± 5.0 0.72 LV ejection fraction (%) 57.7 ± 5.5 57.4 ± 5.2 0.57 RV-TDI s' 12.9 ± 2.93 11.8 ± 3.06 0.47 RV free wall longitudinal strain (%) 18.1 ± 3.4 22.9 ± 3.7 < 0.001 RV global longitudinal strain (%) 20.4 ± 2.4 21.9 ± 2.9 < 0.001 Six-minute walk test (m) 326 ± 42.2 355 ± 57.1 < 0.001 mMRC score 1.8 ± 0.8 1.7 ± 0.7 0.14 BODE index 3.0 ± 2.1 2.8 ± 1.9 0.04 Data are presented as mean ± standard deviation. Bold values indicate statistical significance p < 0.05. RV: right ventricle; RA: right atrium; sPAP: systolic pulmonary artery pressure; TAPSE: tricuspid annular plane systolic excursion; MPI: myocardial performance index; LV: left ventricle; TDI s’: tissue Doppler imaging systolic excursion; mMRC; modified medical research council, BODE; Body mass index, degree of Obstruction (FEV 1 ), Dyspnea score (mMRC scale), Exercise capacity (six minute walk distance). 378