ABC | Volume 111, Nº2, August 2018

Original Article Rodrigues et al Physical exercise and calcium regulation Arq Bras Cardiol. 2018; 111(2):172-179 Figure 4 – Intracellular Ca 2+ transient levels in cardiomyocytes of normotensive and hypertensive animals. (A) Amplitude of intracellular calcium. (B) Time to peak intracellular calcium. (C) Time to 50% decay of intracellular calcium. SN, sedentary normotensive; TN, trained normotensive; SH, sedentary hypertensive; TH, trained hypertensive. Data as mean ± SD of 40-50 cells in each group. * compared with SN; & compared with TN; # compared with SN; + compared with TH (p < 0.05). SN SH TN TH SN SH TN TH SN SH TN TH Amplitude (Fura 340/380) Time to peak (ms) Time to 50% decay (ms) A C B #+ *# *&+ *& *&# * * *+ # 1.0 0.8 0.6 0.4 0.2 0.0 80 60 40 20 0 200 250 150 100 50 0 Figure 5 – MicroRNA-214 expression in the left ventricle in normotensive and hypertensive animals. SN: sedentary normotensive; TN: trained normotensive; SH: sedentary hypertensive; TH: trained hypertensive. Data as mean ± SD of 5 animals in each group. * compared with SN; & compared with TN; # compared with SN (p < 0.05). SN SH TN TH *&# 800 600 400 200 0 Level of MicroRNA-214 (% control) 177