ABC | Volume 111, Nº1, July 2018

Short Editorial Martinez & Okoshi Genetic risk in coronary artery disease Arq Bras Cardiol. 2018; 111(1):62-63 1. Erdmann J, Kessler T, Munoz Venegas L, Schunkert H. A decade of genome- wide association studies for coronary artery disease: The challenges ahead. Cardiovasc Res. Mar 30. [Epub ahead of print]. 2. Myers RH, Kiely DK, Cupples LA, Kannel WB. Parental history is an independent risk factor for coronary artery disease: the framingham study. AmHeart J. 1990;120(4):963-9. 3. Nabel EG. Principles of cardiovascular molecular biology and genetics. In: Bonow RO, Mann DL, Zipes DP, Libby P. (editors). Braunwald’s heart disease. a textbook of cardiovascular disease. Philadelphia: Elsevier Saunders; 2012. p. 57-69. 4. McPherson R, Tybjaerg-Hansen A. Genetics of coronary artery disease. Circ Res. 2016;118(4):564-78. 5. Björkegren JLM, Kovacic JC, Dudley JT, Schadt EE. Genome-wide significant loci: How important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders. J AmColl Cardiol. 2015;65(8):830-45. 6. Borghini A, Andreassi MG. Genetic polymorphisms offer insight into the causal role of microrna in coronary artery disease. Atherosclerosis. 2018 Feb;269:63-70. 7. Pereira A, MendoncaMI, Borges S, Freitas S, Henriques E, RodriguesM, et al. Genetic risk analysis of coronary artery disease in a population-based study in portugal, using a genetic risk score of 31 variants. Arq Bras Cardiol. 2018; 111(1):50-61. 8. Zhao C, Zhu P, Shen Q, Jin L. Prospective association of a genetic risk score with major adverse cardiovascular events in patients with coronary artery disease. Medicine (Baltimore). 2017;96(51):e9473. 9. Guo Y,Wang F, Li L, GaoH, Arckacki S,Wang IZ, et al. Genome-wide linkage analysis of large multiple multigenerational families identifies novel genetic loci for coronary artery disease. Sci Rep. 2017;7(1):5472. 10. Yao C, Chen BH, Joehanes R, Otlu B, Zhang X, Liu C, et al. Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes. Circulation. 2015;131(6):536-49. 11. Howson JM, Zhao W, Barnes DR, Ho WK, Young R, Paul DS, et al. Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms. Nat Genet. 2017;49(7):1113-9. 12. LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, et al. Identifying novel gene variants in coronary artery disease and shared genes with several cardiovascular risk factors. Circ Res. 2016;118(1):83-94. 13. Fairoozy RH, White J, Palmen J, Kalea AZ, Humphries SE. Identification of the functional variant(s) that explain the low-density lipoprotein receptor (LDLR) GWAS SNP rs6511720 association with lower LDL-C and risk of CHD. PLoS One. 2016;11(12):e0167676. References This is an open-access article distributed under the terms of the Creative Commons Attribution License 63