ABC | Volume 110, Nº6, June 2018

Viewpoint Santos Impact of consumption of whole eggs on lipids Arq Bras Cardiol. 2018; 110(6):585-587 1. Ginsberg HN, KarmallyW, Siddiqui M, Holleran S, Tall AR, BlanerWS, et al. Increases in dietary cholesterol are associatedwithmodest increases in both LDL and HDL cholesterol in healthy young women. Arterioscler Thromb Vasc Biol. 1995;15(2):169-78. PMID: 7749822. 2. Edington J, Geekie M, Carter R, Benfield L, Fisher K, Ball M, et al. Effect of dietary cholesterol on plasma cholesterol concentration in subjects following reduced fat, high fibre diet. Br Med J (Clin Res Ed). 1987;294(6568):333-6. PMID: 3028545. 3. Griffin BA. Eggs: good or bad? Proc Nutr Soc. 2016;75(3):259-64. doi: 10.1017/S0029665116000215. 4. Fernandez ML. Rethinking dietary cholesterol. Curr Opin Clin Nutr Metab Care. 2012;15(2):117-21. doi: 10.1097/MCO.0b013e32834d2259. 5. Díez-Espino J, Basterra-Gortari FJ, Salas-Salvadó J, Buil-Cosiales P, Corella D, Schröder H, et al; PREDIMED Investigators. Egg consumption and cardiovascular disease according to diabetic status: the PREDIMED study. Clin Nutr. 2017;36(4):1015-21. doi: 10.1016/j.clnu.2016.06.009. 6. DiMarcoDM, Norris GH, Millar CL, Blesso CN, FernandezML. Intake of up to 3 eggs per day is associated with changes in HDL function and increased plasma antioxidants in healthy, young adults. J Nutr. 2017;147(3):323-9. doi: 10.3945/jn.116.241877. 7. McNamara DJ. The impact of egg limitations on coronary heart disease risk: do the numbers add up? J Am Coll Nutr. 2000;19(5 Suppl):540S-548S. PMID: 11023005. 8. Miranda JM, Anton X, Redondo-Valbuena C, Roca-Saavedra P, Rodriguez JA, Lamas A, et al. Egg and egg-derived foods: effects on human health and use as functional foods.Nutrients.2015;7(1):706-29.doi:10.3390/nu7010706. 9. Knopp RH, Retzlaff BM, Walden CE, Dowdy AA, Tsunehara CH, Austin MA, et al. A double-blind, randomized, controlled trial of the effects of two eggs per day in moderately hypercholesterolemic and combined hyperlipidemic subjects taught the NCEP step I diet. J Am Coll Nutr. 1997;16(6):551-61. PMID: 9430083. 10. Spence JD, Jenkins DJ, Davignon J. Egg yolk consumption and carotid plaque. Atherosclerosis. 2012;224(2):469-73. doi: 10.1016/j. atherosclerosis.2012.07.032. 11. Reddy ST, Wadleigh DJ, Grijalva V, Ng C, Hama S, Gangopadhyay A, et al. Human paraoxonase-3 is anHDL-associated enzymewith biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol. 2001;21(4):542-7. PMID: 11304470. 12. DiDonato JA, Huang Y, Aulak K, Even-Or O, Gerstenecker G, Gogonea V, et al. The Function andDistribution of Apolipoprotein A1 in the ArteryWall are Markedly Distinct from those in Plasma. Circulation. 2013;128(15):1644- 55. doi: 10.1161/CIRCULATIONAHA.113.002624 13. Krauss RM. Dietary and genetic probes of atherogenic dyslipidemia. Arterioscler Thromb Vasc Biol. 2005;25(11):2265-72. doi: 10.1161/01. ATV.0000186365.73973.f0. 14. Xavier HT, Izar MC, Faria Neto JR, Assad MH, Rocha VZ, Sposito AC, et al; Sociedade Brasileira de Cardiologia. [V Brazilian Guidelines on Dyslipidemias and Prevention of Atherosclerosis]. Arq Bras Cardiol. 2013;101(4 Suppl 1):1-20. doi: http://dx.doi.org/105935/abc20135010. 15. Sacks FM, Lichtenstein AH,Wu JH, Appel LJ, Creager MA, Kris-Etherton PM, et al; American Heart Association. Dietary fats and cardiovascular disease: a presidential advisory from the American Heart Association. Circulation. 2017;136(3):e1-e23. doi: 10.1161/CIR.0000000000000510. 16. Office of Disease Prevention and Health Promotion (ODPHP). Advisory Report. Report Index. [Internet]. [Accessed in 2017 Jun 24]. Available from: https://health.gov/dietaryguidelines/2015-scientific-report/ 17. Hunter PM, Hegele RA. Functional foods and dietary supplements for the management of dyslipidaemia. Nat Rev Endocrinol. 2017;13(5):278-88. doi: 10.1038/nrendo.2016.210. 18. GoodrowEF,WilsonTA,HoudeSC,VishwanathanR,ScollinPA,Handelman G, et al. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrations. J Nutr. 2006;136(10):2519-24. PMID: 16988120. 19. Bach-Faig A, Berry EM, Lairon D, Reguant J, Trichopoulou A, Dernini S, et al; Mediterranean Diet Foundation Expert Group. Mediterranean diet pyramid today. Science and cultural updates. Public Health Nutr. 2011;14(12A):2274-84. doi: 10.1017/S1368980011002515. References This is an open-access article distributed under the terms of the Creative Commons Attribution License Taken together, dietary cholesterol mainly by using the egg as a source can alter the lipid profile by increasing the markers in general. However, in assessing the actual biological impact this appears to be practically insignificant. Genetic factors can increase the cholesterol, LDL and triglycerides levels of individuals because of higher cholesterol intake, but nonetheless not quite alarming. Author contributions Conception and design of the research, Acquisition data, Analysis and interpretation of the data, Writing of the manuscript and Critical revision of the manuscript for intellectual content: Santos HO. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. 587

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