ABC | Volume 110, Nº5, May 2018

Case Report Surgical Epicardial CRT-D Implantation in a Patient with Complete Obstruction of the Superior Vena Cava Gustavo Lima da Silva, Nuno Cortez-Dias, João de Sousa, Ângelo Nobre, Fausto J. Pinto Centro Hospitalar Lisboa Norte, Hospital de Santa Maria, Lisboa - Portugal Mailing Address: Gustavo Lima Sousa da Silva • Serviço de Cardiologia, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte. Av. Prof. Egas Moniz. 1649-035, Lisboa - Portugal E-mail: gustavolssilva@gmail.com Manuscript received February 14, 2017, revised manuscript May 28, 2017, accepted July 03, 2017 Keywords Heart Failure; Tachycardia, Ventricular; Vena Cava, Superior / physiopathology; Cardiac Resynchronization Therapy Devices; Cardiovascular Surgical Procedures. DOI: 10.5935/abc.20180070 Introduction Current guidelines clearly define the subset of heart failure patients who benefit from device implantation. 1 Although first-time trans-venous device implantation has a high success rate, some patients present complex and challenging technical problems. 2 Case Report We present a case of a 73-year-old male patient admitted to our cardiology department for acute heart failure and two episodes of monomorphic ventricular tachycardia with hemodynamic collapse. Eight years previously the patient was diagnosed with class NYHA II heart failure, non‑ischemic dilated cardiomyopathy with 32% left ventricle (LV) ejection fraction and complete left bundle branch block. After optimized medical therapy, he underwent conventional CRT-D implantation through the left subclavian (SC) vein in another institution. Two years later defibrillator lead fracture was diagnosed. The lead was abandoned and another defibrillator lead was implanted through the right SC vein and further tunneled subcutaneously to reach the left-sided prepectoral pocket. The procedure was complicated with superior vena cava thrombosis and device infection and the patient underwent right defibrillator lead and generator extraction. The previously implanted right atrial lead, fractured defibrillator lead and LV pacing lead were abandoned. One year later the patient was diagnosed with complete heart block and was submitted to epicardial mono-chamber pacemaker (VVI-R) implantation with supra‑peritoneal epigastrium pouch (Figure 1C). On admission at our department, 12 lead electrocardiogram (Figure 1A) showed sinus P waves with dissociated right ventricular epicardial pacing (Vp). Device interrogation revealed 99% Vp. Echocardiographic evaluation showed a dilated LV with severely depressed ejection fraction (20%) due to diffuse hipokinesia. Coronary angiogram confirmed the absence of coronary disease. Venous angio computed tomography demonstrated complete obstruction of the superior vena cava drainage system and severe fibrosis around the abandoned leads. A surgical off-pump complete epicardial CRT-D implantation was decided. A median sternotomy was performed and complete epicardial CRT-D implantation was accomplished with a Starfish ® 2 heart positioner aid. The previously implanted epicardial mono-chamber pacemaker was extracted. A sutured bipolar lead [Capsure® Epi 4968 (Medtronic Inc., Minneapolis, Minnesota, USA)] was placed in the lateral wall of the right atrium (RA) and two sutureless screw-in bipolar leads (MyoDex® 1084T [St. Jude Medical Inc., Little Canada, Minnesota, USA]) were placed in the right ventricular outflow tract (RVOT) and lateral LV wall. Two defibrillator epicardial sutured patches were implanted in the anterior and posterior surface of the heart (Figure 1D). All these leads were then tunnelled to a left sided pre pectoral pocket and connected to the generator [Brava® CRT-D (Medtronic Inc., Minneapolis, Minnesota, USA)] – Figure 1E. Acute pacing parameters were excellent (RA – 1 mv/0,4 ms; RVOT – 2,5 mV/0,5 ms; LV - 2,5 mV/1,5 ms). Defibrillation testing was performed was performed at the time of implantation. Induced ventricular fibrillation was appropriately detected with successful defibrillation at 25J (Figure 1B, 1F). The patient remained for 24 hours in the intensive care unit and was thereafter transferred to the cardiology ward where he remained for 7 days before discharge under optimized medical therapy. Discussion There were three alternative percutaneous approaches to complete CRT-D implantation in the presented patient: 1) lead extraction and left sided implantation; 2) implantation through the inferior vena cava system; 3 3) sub-xiphoid epicardial implantation. 4,5 The Heart Team considered lead extraction unfeasible due to complete obstruction of the superior venous system and severe fibrosis around the abandoned leads. Implantation through the ileo-femoral vein and inferior vena cava system was considered high risk as it was the only venous draining site to the heart. Also, defibrillating vectors would be inadequate and the risk of lead dislodgement and infection high. Percutaneous sub-xiphoid epicardial access was considered unfeasible due to the presence of the previous epicardial pacemaker. In addition, supra-peritoneal generator placement would also produce inadequate defibrillating vectors. Epicardial pacing and defibrillator systems have long existed and defibrillator coils are though to offer better long-term outcomes than defibrillator patches due to the high rate of patch crinkling (36-54%). 6 This is associated with leadmalfunction and chronic chest pain. However, access to epicardial defibrillator material is particularly difficult and in some countries only defibrillator patches are approved for epicardial usage. 490