ABC | Volume 110, Nº5, May 2018

Original Article Salmazo et al Frequency of subclinical atherosclerosis in Brazilian HIV-infected patients Arq Bras Cardiol. 2018; 110(5):402-410 Figure 2 – Association between carotid intima-media thickness and age in the control and HIV-infected group. 1.4 1.2 1.0 0.8 0.6 0.4 0.2 10 20 30 40 50 60 70 80 Age (years) HIV Controls Carotid intima-media thickness (mm) HIV: In (y) = 0.013x-0.985 Controls: In (y) = 0.009x-0.816 p < 0.001 Figure 3 – Association between pulse wave velocity and systolic blood pressure (panel A) and age (panel B). Panel A Panel B In(y) = 1.492 + 0.011 age R = 0.557 p < 0.001 R = 0.573 p < 0.001 Pulse wave velocity (m/s) Pulse wave velocity (m/s) Systolic blood pressure Age (years) 16 14 12 10 8 6 4 2 80 100 120 140 160 180 200 16 14 12 10 8 6 4 2 20 30 40 50 60 70 80 Plaques were found in 37% of the HIV-infected individuals, slightly lower than the 55% reported in some publications. 18,19,37 This study found that the presence of HIV produced an almost fivefold increase in the risk of carotid PL in the model adjusted for age, overweight/obesity, and smoking. We may therefore suppose that the presence of HIV infection is a contributory factor to the development of atherosclerosis, in addition to the traditional risk factors, and in agreement with other studies. 10,11,15,18,38 There was no association between the presence of carotid PL and time since diagnosis or treatment duration, abdominal circumference, BMI, HDL-c, and CD4 + or CD8 + cell count. 406