ABC | Volume 110, Nº4, April 2018

Brief Communication De Santi et al Aerobic training and LV contractility post-MI Arq Bras Cardiol. 2018; 110(4):383-387 in cardiac function and maintenance of cavitary volumes. Kubo et al., 5 observed an increase in cavitary volumes and maintenance of cardiac function. Giallauria et al., 6 documented maintenance of both cavitary volumes and cardiac function. In the present study, the cavitary volumes and the cardiac function estimated by left ventricle ejection fraction did not present statistically significant changes. Moreover, in this way, they were not able to identify different patterns of ventricular remodeling in the training groups compared to the CG. From the point of view of functional capacity, we observed a comparable increase of 14% in ITG and MTG VO 2 peak. We used the 4x4 aerobic interval training model recommended in several studies for promoting expressive increases in VO 2 peak, compared to continuous moderate aerobic training. 10,11 However, we did not show a statistically significant difference between the ITG and the MTG VO 2 peak, after the period of physical training. We highlight that the present study data are corroborated by SAINTEX-CAD Study findings that showed a similar increase in physical fitness, comparing interval aerobic training versus continuous moderate aerobic training, in a large casuistry of patients with coronary artery disease. 12 Study limitations It is known that HR increases linearly with VO 2 within defined limits in the bands of 50 to 90% maximum VO 2 . However, in the present study, we could not establish a relationship between training intensity and ventilatory thresholds. Finally, the area of fibrosis was not analyzed. The extension of fibrosis in the infarction area infarction can be an important determinant of the results of AFT in myocardial deformation parameters and ventricular rotation. Conclusions The findings of this study point to a potential clinical application of ventricular contraction mechanics parameters analysis, notably radial strain, in discriminating post-infarction myocardial adaptations between patients submitted or not to aerobic training programs. Author contributions Conception and design of the research: De Santi GL, Schmidt A, Gallo-Júnior L; Acquisition of data: De Santi GL, Moreira HT, Carvalho EEV, Crescêncio JC; Analysis and interpretation of the data: De Santi GL, Moreira HT, Carvalho EEV, Schmidt A, Marin Neto JA, Gallo-Júnior L; Statistical analysis: De Santi GL, Crescêncio JC; Writing of the manuscript: De Santi GL, Gallo-Júnior L; Critical revision of the manuscript for intellectual content: Marin Neto JA, Gallo-Júnior L. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This article is part of the thesis of Doctoral submitted by Giovani Luiz De Santi, from Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo under the protocol number 11612/2008. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 1. Shaw SM, Fox DJ, Williams SG. The development of left ventricular torsion and its clinical relevance. Int J Cardiol. 2008;130(3):319-25. doi: 10.1016/j. ijcard.2008.05.061. 2. Mor-Avi V, Lang RM, Badano LP, Belohlavek M, Cardim NM, Derumeaux G, et al. Current and evolving echocardiographic techniques for the quantitativeevaluationofcardiacmechanics:ASE/EAEConsensusStatement on Methodology and Indications. Endorsed by the Japanese Society of Echocardiography. J Am Soc Echocardiogr. 2011;24(3):277-313. doi: 10.1016/j.echo.2011.01.015. 3. Ghorayeb N, Costa RV, Daher DJ, Oliveira Filho JA, Oliveira MA, et al. [Guidelines on exercise and sports cardiology from the Brazilian Society of Cardiology and the Brazilian Society of Sports Medicine]. Arq Bras Cardiol. 2013;100(1 Suppl 2):1-41. doi: http://dx.doi.org/10.5935/abc.2013S002. Erratum in: Arq Bras Cardiol. 2013;100(5):488. 4. Giannuzzi P, Temporelli PL, Corra U, Gattone M, Giordano A, Tavazzi L. Attenuation of unfavorable remodeling by exercise training in postinfarction patients with left ventricular dysfunction: results of the Exercise in Left Ventricular Dysfunction (ELVD) trial. Circulation. 1997;96:1790-1797. PMID: 9323063. References 386

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