ABC | Volume 110, Nº4, April 2018

Original Article Cardoso et al Infection in patients with heart failure Arq Bras Cardiol. 2018; 110(4):364-370 Table 4 – Comparison of the characteristics of the patients regarding total mortality (in-hospital + post-discharge) Characteristics Total Death p* Yes (n = 92) No (n = 168) Age (years) 65.9 ± 12.4 66.2 ± 12.9 0.828 Male sex – n (%) 55 (59.8) 86 (51.2) 0.184 HF etiology – n (%) Chagasic 21 (22.8) 25 (14.9) 0.108 Ischemic 31 (33.7) 66 (39.3) 0.373 Comorbidities – n (%) Renal failure 64 (69.6) 78 (46.4) <0.001 COPD 10 (10.9) 24 (14.3) 0.435 Hypothyroidism 17 (18.5) 30 (17.9) 0.901 Diabetes mellitus 28 (30.4) 67 (39.9) 0.130 Atrial fibrillation 47 (51.1) 72 (42.9) 0.203 Urinary infection 14 (15.2) 25 (14.9) 0.942 Pneumonia 31 (33.7) 57 (33.9) 0.970 Infection (urinary and/or pulmonary) 42 (45.7) 77 (45.8) 0.978 Vital signs: SBP (mm Hg) 91 (84-110) 100 (82-125) 0.023 DBP (mm Hg) 60 (57.5-70) 63.5 (55-80) 0.465 HR (bpm) 80 (69.5-100) 80 (70-94.5) 0.898 Echocardiogram: LVDD (mm) 64.0 ± 9.4 61.0 ± 10.8 0.029 LA (mm) 48.3 ± 7.3 48.5 ± 7.1 0.859 LVEF (%) 28.5 (24.25-35) 35 (25-49) 0.002 PAP (mm Hg) 54.2 ± 15.8 49.8 ± 15.3 0.058 Hemodynamic profile – admission – n (%) Profile B 37 (40.2) 94 (56.0) 0.015 Profile C 50 (54.3) 61 (36.3) 0.005 Profile L 5 (5.4) 13 (7.7) 0.484 Laboratory tests Hemoglobin 12.4 ± 2.1 13.5 ± 2.3 < 0.001 Urea (mg/dL) 82 (54-114) 74.5 (51-107) 0.453 Creatinine (mg/dL) 1.66 (1.23-2) 1.54 (1.22-2.03) 0.481 Sodium 137 (134-139) 138 (135-140) 0.325 Potassium 4.3 (4-4.9) 4.4 (4-4.8) 0.835 C-reactive protein 17.97 (8.94-48.8) 18.88 (7.31-60.42) 0.927 CKMB mass 1.98 (1.32-3.26) 2.1 (1.5-3.6) 0.759 Troponin I 0.05 (0.02-0.11) 0.05 (0.02-0.1) 0.941 BNP 1274 (774-2095) 969 (383.5-1951.5) 0.098 Total cholesterol 138.0 ± 44.9 147.0 ± 46.2 0.306 HDL 32.6 ± 15.0 39.1 ± 15.0 0.013 LDL 83.5 ± 35.8 87.1 ± 36.5 0.499 Vasoactive drugs on admission – n (%) Dobutamine 72 (78.3) 87 (51.8) < 0.001 Levosimendan 6 (6.5) 12 (7.1) 0.850 Milrinone 5 (5.4) 4 (2.4) 0.286 Data are presented as mean ± standard deviation for continuous variables with normal distribution, or median (interquartile range 25% - 75%) for continuous variables with non-normal distribution. Categorical variables are presented as absolute numbers (percentage). P*: To calculate P value, Student t test was used for the variables with normal distribution, Mann-Whitney U test for the variables with non-normal distribution. P value was estimated by use of the chi-square test or Fisher exact test for the categorical variables. COPD: chronic obstructive pulmonary disease; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; LVDD: left ventricular diastolic diameter; LA: left atrium; LVEF: left ventricular ejection fraction; PAP: pulmonary artery pressure. 369