ABC | Volume 110, Nº4, April 2018

Original Article Dong et al Comparison between HCR and OPCAB Arq Bras Cardiol. 2018; 110(4):321-330 Some limitations of the present analysis should be also emphasized. Firstly, all included studies belong to observational studies and no single RCT has been conducted so far. Secondly, some included studies contain relatively small samples (fewer than 50 patients) and remain imbalance of patient number between groups so that deviation of results may inevitably exist. Thirdly, long-term patency is more convincing than short-term and mid-term outcomes, but very limited references were published with long-term follow-up so far. Finally, some uncontrolled factors may interfere with the current analysis. Variables like gender ratio and LVEF at baseline have not been adjusted. And diverse surgery procedures, stents (DES or bare stent) as well as antiplatelet strategies may disturb the accuracy of results too. Conclusions HCR shows similar results with OPCAB in short-term clinical outcomes. HCR decreases the ventilator time, ICU stay, hospital stay, blood transfusion rate and increases the operation time and hospitalization costs. Although repeated vessel revascularization is greater with HCR, it has a lower mid‑term MACCE rate and could provide a safe and reproducible alternative for patients with multivessel CAD. Author contributions Conception and design of the research and Critical revision of themanuscript for intellectual content: Xiang-guang A; Acquisition of data, Analysis and interpretation of the data, Statistical analysis and Writing of the manuscript: Li D, Yi-kun K. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. 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