ABC | Volume 110, Nº4, April 2018

Original Article Dong et al Comparison between HCR and OPCAB Arq Bras Cardiol. 2018; 110(4):321-330 Table 1 – Characteristics of the included studies References Year Primary endpoint Follow-up HCR OPCAB Number of patients Mean age Baseline LVEF (%) Setting Surgery type Stents Antiplatelet strategy Number of patients Mean age Baseline LVEF (%) Kon 18 2008 In-hospital MACCE 1 year 15 61.0 ± 10.0 47.0 ± 14.0 Simultaneous Small thoracotomy DES Aspirin 325 mg, clopidogrel 300 mg 30 65.0 ± 10.0 45.0 ± 14.0 Vassiliades 19 2009 In-hospital mortality 1 year 91 64.7 ± 13.7 51.5 ± 9.4 Staged Endo-ACAB DES (85.8%) Aspirin 81-162 mg, clopidogrel 75 mg 4175 62.8 ± 11.7 50.9 ± 12.7 Hu 20 2010 In-hospital MACCE Mean 18 months 104 61.8 ± 10.2 62.4 ± 6.9 Simultaneous Ministernotomy DES Aspirin 100 mg, clopidogrel 300 mg 104 62.4 ± 8.0 63.4 ± 7.5 Halkos 21 2011 In-hospital MACCE Median 3.2 years 147 64.3 ± 12.8 54.6 ± 8.7 Staged Endo-ACAB with robotic assistance DES (mojority) Clopidogrel 600 mg 588 64.3 ± 12.5 54.7 ± 8.7 Halkos 22 2011 In-hospital and 30-day MACCE Median 3.2 years 27 63.9 ± 13.7 56.6 ± 7.7 Staged Mini-sternotomy, robotic assistance DES (92.6%) Clopidogrel 600 mg 81 63.9 ± 12.7 56.6 ± 7.6 Bachinsky 23 2012 In-hospital and 30-day MACCE 30 days 25 63.2 ± 10.5 55.3 ± 10.4 Staged Thoracotomy with robotic assistance DES (71.0%) Aspirin 325 mg, clopidogrel 600 mg 27 66.8 ± 10.7 51.5 ± 12.0 Zhou 24 2013 In-hospital MACCE 30 days 141 62.0 ± 10.1 61.8 ± 6.9 Simultaneous Mini-sternotomy DES Aspirin 100 mg, heparin 120 IU/kg 141 63.2 ± 8.5 60.1 ± 9.3 Harskamp 25 2014 cTnI after 24h 1 year 33 65.0 ± 6.5 55.0 ± 7.5 Simultaneous Mini-thoracotomy with robotic assistance DES (75.8%) Aspirin and clopidogrel 32 67.0 ± 7.0 55.0 ± 5.0 Song 26 2016 In-hospital outcomes Median 2.5 years 120 62.3 ± 9.4 63.9 ± 7.3 Simultaneous Mini-sternotomy DES (99.5%) Aspirin 100 mg, clopidogrel 300 mg 240 62.8 ± 8.4 64.2 ± 6.9 MACCE: major adverse cardiac and cerebrovascular event, cTnI: cardiac troponin I, HCR: hybrid coronary revascularization, OPCAB: Off-pump coronary artery bypass grafting, LVEF: left ventricular ejection fraction, endo‑ACAB: endoscopic atraumatic coronary artery bypass, DES: drug-eluting stent. 324