ABC | Volume 110, Nº3, March 2018

Original Article Xu et al Association of severity of coronary lesions with BMD Arq Bras Cardiol. 2018; 110(3):211-216 1. Uppoor RB, Rajesh A, Srinivasan MP, Unnikrishnan B, Holla R. Oxidative stress in obese postmenopausal women: an additive burden for atherosclerosis. J Clin Diagn Res. 2015;9(12):OC03-5. doi: 10.7860/ JCDR/2015/16467.6868. 2. Dou KF, Xu B, Yang YJ, Lu R, QiuH, YangWX, et al. Clinical and angiographic characteristics of premenopausal womenwith coronary artery disease. Chin Med J (Engl). 2008;121(23):2392-6. PMID: 19102955. 3. Calvo RY, Araneta MR, Kritz-Silverstein D, Laughlin GA, Barrett-Connor E. Relation of serum uric acid to severity and progression of coronary artery calcium in postmenopausal White and Filipino women (from the Rancho Bernardo study). Am J Cardiol. 2014;113(7):1153-8. doi: 10.1016/j. amjcard.2013.12.022. 4. Kocic R, Spirovski D, Ciric V, Velija-Asimi Z. 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Coexistence of osteoporosis (OP) and coronary artery disease (CAD) in the elderly: it is not just a by chance event. Arch Gerontol Geriatr. 2012;54(3):473-6. doi: 10.1016/j.archger.2011.06.007. 17. Seo SK, Yun BH, Noe EB, Suh JW, Choi YS, Lee BS. Decreased bone mineral density is associated with coronary atherosclerosis in healthy postmenopausal women. Obstet Gynecol Sci. 2015;58(2):144-9. doi: 10.5468/ogs.2015.58.2.144. 18. Sinning C, Lillpopp L, Appelbaum S, Ojeda F, Zeller T, Schnabel R, et al. Angiographic score assessment improves cardiovascular risk prediction: the clinical value of SYNTAX and Gensini application. Clin Res Cardiol. 2013;102(7):495-503. doi: 10.1007/s00392-013-0555-4. References Conclusion In this study, we investigated the association between BMD and severity of coronary lesions in postmenopausal women. Our results suggested postmenopausal women with low BMD are at high risk for severe coronary lesions. Future research should investigate common pathophysiological pathways between osteoporosis and severity of coronary lesions. Author contributions Conception and design of the research: Xu R, Xin‑Chun C, Hong-Ni Y; Acquisition of data and Analysis and interpretation of the data: Xu R, Zhang Y, Hong‑Mei L; Statistical analysis: Xu R; Writing of the manuscript: Xin‑Chun C; Critical revision of the manuscript for intellectual content: Xu R, Hong-Ni Y. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding There were no external funding sources for this study. Study Association This study is not associatedwith any thesis or dissertationwork. Ethics approval and consent to participate This study was approved by the Ethics Committee of the People’s Hospital of Xinjiang Uyghur Autonomous Region under the protocol number 678999009. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 215