ABC | Volume 110, Nº2, February 2018

Review Article Perrier-Melo et al Interval exercise in heart transplant recipients Arq Bras Cardiol. 2018; 110(2):188-194 Table 2 – Characteristics of the sample, methodological quality and major results of the studies assessing the effect of high-intensity interval training (HIIT) on heart transplant (HTx) recipients. Study GROUPS HIIT protocol Duration (weeks) Major results Testex HIIT CONTROL 1 2 3 4 5 6 6 6 7 8 8 9 10 11 12 Haykowsky et al., 2009 N = 22 17M/5F 57 ± 10 Post-HTx time = 5.4 ± 4.9 years N = 21 18M/3F 59 ± 11 Post-HTx time = 4.4 ± 3.3 years Cycle ergometer and treadmill 1-8 weeks 5x/week 30-45 min: 60-80%VO 2 peak 5x/week 12 weeks 12 weeks of training significantly increased VO 2 peak (21.2 ± 7.3 - 24.7 ± 8.8 mL/kg/min, p = 0.003) of HTx recipients + + + + + + + + + + 9-12 weeks 3x/weeks 30-45 min: 60-80%VO 2 peak 2x/weeks 20-25x (30s: 90-100% VO 2 peak/1 min) Hermann et al., 2011 N = 14 12M/2F 53 ± 11 Post-HTx time = 6.8 ± 4.0 years N = 13 10M/3F 47 ± 18 Post-HTx time = 7.0 ± 5.5 years Cycle ergometer and staircase running 4 min: 80% VO 2 peak / ½ min 2 min: 85% VO 2 peak / ½ min 30 s: 90% VO 2 peak / ½ min 3x/week 8 weeks The 8-week HIIT program significantly reduced SBP (p = 0.02) and significantly increased VO 2 peak (p < 0.001) and endothelial action + + + + + + + + + + Nytroen et al., 2012 N = 24 16M/8F 48 ± 17 Post-HTx time = 4.3 ± 2.4 years N = 24 17M/7F 53 ± 14 Post-HTx time = 3.8 ± 2.1 years Treadmill 4 min (85-95% HRmax) / 3 min (11-13 Borg SEP) 3x/week 8 weeks HIIT significantly improved VO 2 peak (p < 0.001) after 8 weeks of training + + + + + + + + + + N: sample; M: male; F: female; HRmax: maximum heart rate; SEP: subjective effort perception; SBP: systolic blood pressure. 191