ABC | Volume 110, Nº1, January 2018

Original Article Cerqueira Junior et al GRACE Score in Octogenarians Arq Bras Cardiol. 2018; 110(1):24-29 1. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation. 1994;90(1):583-612. PMID: 8026046. 2. Roe MT, Messenger JC, Weintraub WS, Cannon CP, Fonarow GC, Dai D, et al. Treatments, trends, and outcomes of acute myocardial infarction and percutaneous coronary intervention. J AmColl Cardiol. 2010;56(4):254-63. doi: 10.1016/j.jacc.2010.05.008. 3. Pieper KS, Gore JM, FitzGerald G, Granger CB, Goldberg RJ, Steg G, et al; Global Registry of Acute Coronary Events (GRACE) Investigators. Validity of a risk-prediction tool for hospital mortality: the Global Registry of Acute Coronary Events. 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References protection versus complications in procedures, the greatest benefit in very elderly may be antagonized by greater incidence of complications. Therefore, we emphasize this age range needs validation of the GRACE Score as for the prediction of benefits of more aggressive therapeutic strategies. This is a gap to be filled by future studies. Conclusion In conclusion, the present study represents a favorable evidence to the accurate use of the GRACE Score in the prediction of in-hospital death among octogenarian and nonagenarian patients hospitalized with ACS. Author contributions Conception anddesignof the research: Cerqueira Junior AMS, Pereira LGS, Souza TMB, Correia VCA, Alexandre FKB, Suerdieck JG, Ferreira F, RabeloMMN, Correia LCL; Acquisition of data: Cerqueira Junior AMS, Pereira LGS, Souza TMB, Correia VCA, Sodré GA, Suerdieck JG, Ferreira F, Correia LCL; Analysis and interpretation of the data: Cerqueira Junior AMS, Pereira LGS, Souza TMB, Correia VCA, Sodré GA, Suerdieck JG, Ferreira F, Rabelo MMN, Correia LCL; Statistical analysis and Writing of the manuscript: Cerqueira Junior AMS, Pereira LGS, Souza TMB, Correia VCA, Alexandre FKB, Sodré GA, Suerdieck JG, Ferreira F, Rabelo MMN, Correia LCL; Obtaining financing: Rabelo MMN, Correia LCL; Critical revision of the manuscript for intellectual content: Cerqueira Junior AMS, Souza TMB, Correia VCA, Alexandre FKB, Sodré GA, Suerdieck JG, Ferreira F, Rabelo MMN, Correia LCL. Potential Conflict of Interest No potential conflict of interest relevant to this article was reported. Sources of Funding This study was partially funded by FAPESB. Study Association This article is part of the thesis of master submitted by Antonio Mauricio dos Santos Cerqueira Junior, from Escola Bahiana de Medicina e Saúde Pública. Ethics approval and consent to participate This study was approved by the Ethics Committee of the Hospital São Rafael under the protocol number 35/11. All the procedures in this study were in accordance with the 1975 Helsinki Declaration, updated in 2013. Informed consent was obtained from all participants included in the study. 28